Browsing by Author "Ávila Jiménez, Eduardo Rodolfo"

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    Clinical and epidemiological characterization of glomerular diseases in chile: a retrospective multicenter observational study
    (2024) Valjalo, Ricardo; Villalobos, Arturo; Ruiz, Andrea; Segura, Paula; Ávila Jiménez, Eduardo Rodolfo; Fulgeri, Celeste; Musalem, Pilar; Müller, Hans; Barrero, David; Cordero, Carolina; Gutiérrez, Rocío; Mallea, María; Contreras, Francisco; Caviedes, César; Año, Agustín; Hernández, María
    Glomerular diseases are the main cause of end-stage chronic kidney disease in the world. Its prevalence varies between regions, with no studies in Chile that characterize them. Our main objective is to evaluate the prevalence of glomerular diseases in the country, analyzing histological studies in a collaborative multicenter effort.
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    Effect of the covid-19 pandemic on the frequency of glomerular diseases in a population with low prevalence of apol1 risk variants : WCN24-2633
    (2024) Valjalo, Ricardo; Villalobos, Arturo; Ruiz, Andrea; Segura, Paula; Ávila Jiménez, Eduardo Rodolfo; Fulgeri, Celeste; Musalem, Pilar; Navarro, Fernando; Pais, Edgard; Cordero, Carolina; Mansilla, Rodrigo; Reynolds, Enrique; Contreras, Francisco; Hellman, Elizabeth; Año, Agustín; Hernández, María
    Different glomerular diseases have been reported in people with COVID-19 and/or after vaccination against SARS-CoV-2, with the development of collapsing FSGS being observed more frequently in populations with high-risk APOL1 genotypes. However, a causal link between glomerular diseases and COVID-19 infection or its vaccine is not firmly established. To evaluate the real impact of the COVID-19 pandemic on the epidemiology of glomerular diseases, we conducted a retrospective multicenter study analyzing the clinical manifestations and histological findings in renal biopsies during the pre-pandemic and pandemic period.
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    Nefropatía aguda por fosfatos secundaria al uso de laxantes con fosfato de sodio: caso clínico-patológico
    (2021) Ávila Jiménez, Eduardo Rodolfo; Purto, Dalay; Kutscher Campero, Sofía; Cornejo Valenzuela, Cristina; Severino Cuevas, Nicolás Felipe; Méndez Olivieri, Gonzalo Patricio; Tagle Vargas, Rodrigo Jaime
    Acute phosphate nephropathy (APN) is an acute renal failure secondary to the use of oral sodium phosphate (OSP) laxatives, with a high risk of progression to chronicity. We report a 60-year-old woman with mixed connective tissue disease whose serum creatinine increased up to 2.0 mg/dL in her regular control tests, without an evident causative factor. Kidney biopsy showed numerous intratubular calcium phosphate deposits, consistent with APN. She had a history of OSP laxative intake, and a sodium phosphate enema was used before a colonoscopy performed six months earlier. The temporal association between the use of OSP laxatives and acute kidney injury, should lead to the suspicion of APN. The urine sediment is generally normal or with mild to moderate proteinuria. The diagnosis is confirmed with a kidney biopsy. Until now, there is no specific treatment for APN, thus prevention is essential. In high-risk patients for developing APN, the administration of these laxatives should be avoided.