Browsing by Author "Bugedo, D."
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- ItemNitrous oxide (N2O) reduces postoperative opioid-induced hyperalgesia after remifentanil-propofol anaesthesia in humans(OXFORD UNIV PRESS, 2011) Echevarria, G.; Elgueta, F.; Fierro, C.; Bugedo, D.; Faba, G.; Iniguez Cuadra, R.; Munoz, H. R.; Cortinez, L. I.Background. The aim of this study was to test if intraoperative administration of N2O during propofol-remifentanil anaesthesia prevented the onset of postoperative opioid-induced hyperalgesia(OIH).
- ItemTidal volume is a major determinant of cyclic recruitment-derecruitment in acute respiratory distress syndrome(EDIZIONI MINERVA MEDICA, 2011) Bruhn, A.; Bugedo, D.; Riquelme, F.; Varas, J.; Retamal, J.; Besa, C.; Cabrera, C.; Bugedo, G.Background. Overdistension and cyclic recruitment-derecruitment contribute to ventilator-induced lung injury. High tidal volumes are thought to increase mortality mainly by inducing overdistension. However, experimental evidence suggests that tidal volume (VT) may also influence cyclic recruitment-derecruitment. Our main goal was to determine whether high tidal volumes increase cyclic recruitment-derecruitment in acute respiratory distress syndrome (ARDS) patients, as measured by dynamic computed tomography (CT).