Browsing by Author "Calderon, Jorge"
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- ItemAn update on neuropsychiatric lupus with emphasis in cognitive dysfunction(SOC MEDICA SANTIAGO, 2012) Leon, Tomas; Henriquez, Carla; Calderon, Jorge; Massardo, LoretoPatients with systemic lupus erythematosus (SLE) suffer from a number of neuropsychiatric (NP) symptoms throughout their disease affecting them both physically and psychologically We review herein the nomenclature and case definitions for neuropsychiatric lupus syndromes proposed by the American College of Rheumatology in 1999. We emphasize cognitive dysfunction and discuss etiological hypotheses, especially those related to the presence of antineuronal autoantibodies. (Rev Med Chile 2012; 140; 1333-1341).
- ItemImpact of Delirium on Short-Term Mortality in Elderly Inpatients: A Prospective Cohort Study(ELSEVIER SCIENCE INC, 2009) Gonzalez, Matias; Martinez, Gabriel; Calderon, Jorge; Villarroel, Luis; Yuri, Francisca; Rojas, Carlos; Jeria, Alvaro; Valdivia, Gonzalo; Marin, Pedro Paulo; Carrasco, MarcelaBackground: Delirium is an important problem especially in older medical inpatients. Objective: The authors asked whether delirium and its duration are associated with higher mortality in a 3-month follow-up period. Method: In this prospective cohort study, inpatients age 65 and older were assessed every 48 hours with the Confusion Assessment Method. Results: Of 542 patients enrolled, 192 (35.4%) developed delirium. After 3 months, mortality in the delirium cohort was 25.9%, and in the nondelirium cohort was 5.8%. Delirium was independently associated with mortality, and increased by 11% for every 48 hours of delirium. Conclusion: Delirium and increased delirium durations are significantly associated with higher mortality. (Psychosomatics 2009; 50: 234-238)