Browsing by Author "Cook, María Paz"
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- ItemCohort Profile : The Maule Cohort (MAUCO)(2020) Ferreccio Readi, Catterina; Huidobro, A.; Cortés Arancibia, Sandra; Bambs S., Claudia; Toro Espinoza, Pablo Esteban; Van De Wyngard, Vanessa; Acevedo Romo, Johanna Patricia; Verdejo Pinochet, Hugo; Cook, María Paz; Castro Gálvez, Pablo Federico; Cruz Olivos, Francisco; Corvalán R., Alejandro; Paredes, F.; Venegas, P.; Oyarzún González, X.; Foerster, C.; Vargas, C.; Koshiol, J.; Araya, J. C.; Quest, A. F.; Kogan, M. J.; Lavandero, S.; MAUCO Study Group
- ItemDistribution of dysplasia and cancer in the gallbladder : an analysis from a high cancer-risk population(2018) Koshiol, Jill; Bellolio, Enrique; Vivallo, Carolina; Cook, María Paz; McGee, Emma E.; Losada, Héctor; Van Dyke, Alison L.; Van De Wyngard, Vanessa; Prado, Rodrigo; Villaseca, Miguel; Riquelme, Pía; Acevedo, Johanna; Olivo, Vanessa; Pettit, Karen; Hildesheim, Allan; Medina, Karie; Memis, Bahar; Adsay, Volkan; Ferreccio Readi, Catterina; Araya, Juan Carlos
- ItemEducación en salud: en la búsqueda de metodologías innovadoras(2011) Barrios Araya, Silvia; Masalan Apip, María Patricia; Cook, María PazLa educación en salud es un proceso complejo que requiere de la incorporación de conocimientos, habilidades, actitudes y valores necesarios para formar profesionales en el área, además de estrategias que permitan una evaluación integral de las competencias adquiridas. El objetivo de este trabajo es determinar el estado del arte existente acerca del uso de metodologías innovadoras en aprendizaje y evaluación para el desarrollo de habilidades clínicas en el área de la salud. La literatura revisada destaca metodologías tales como Examen Clínico. Objetivo Estructurado, Instrucción y aprendizaje con ayuda computacional, Programas de aprendizaje basados en Internet, Programas basados en computación Multimedia, y Simulación de realidad virtual, cuyo enfoque educativo permite a los estudiantes de enfermería aplicar e integrar los conocimientos recién adquiridos con la experiencia clínica, de manera de generar mayor seguridad y confianza previo a la llegada al paciente verdadero. Estos métodos favorecen la autoconfianza en los estudiantes al ser tecnologías que propician el aprendizaje en un entorno seguro, provocando altos niveles de rendimiento clínico, académico y en la satisfacción con el curso. Además, estas tecnologías permiten el desarrollo de estrategias cognoscitivas superiores, más que la adquisición de solo conocimiento, lo que a la larga fomenta el logro de competencias. La implementación de tecnologías de este tipo requiere del fortalecimiento de los equipos de trabajo para la planificación e implementación de cambios. Sin embargo, las experiencias de simulación en un laboratorio nunca reemplazarán las experiencias clínicas con pacientes verdaderos.
- ItemEstudio de metales urinarios y plomo en sangre : parámetros poblacionales en Antofagasta, 2018(2020) Ríos Bustamante, Juan Carlos; Villarroel del Pino, Luis A.; Torres Hidalgo, Marisa; Astaburuaga, J. P.; Leiva, C.; Cook, María Paz; Medel Jara, Patricio Andrés; Cortés Arancibia, Sandra; CEDEUS (Chile)
- ItemExamen de detección de virus papiloma humano en el tamizaje de cáncer cervicouterino en un Servicio de Salud de Santiago, Chile(2015) Terrazas, Solana; Ibáñez Cáceres, Carolina; Lagos, Marcela; Poggi, Helena; Brañes, Jorge; Barriga Cosmelli, María Isabel; Cartagena, Jaime; Núñez, Felipe; González, Francisca; Cook, María Paz; Van De Wyngard, Vanesa; Ferreccio Readi, Catterina; Terrazas, Solana; Ibáñez Cáceres, Carolina; Lagos, Marcela; Poggi, Helena; Brañes, Jorge; Barriga, María I.; Cartagena, Jaime; Núñez, Felipe; González, Francisca; Cook, María Paz; Van De Wyngard, Vanesa; Ferreccio Readi, Catterina
- ItemHPV16/18 genotyping for the triage of HPV positive women in primary cervical cancer screening in Chile(2015) Lagos Lucero, Marcela; Van De Wyngard, Vanessa; Poggi, Helena; Cook, María Paz; Viviani García, Paola; Barriga Cosmelli, María Isabel; Ferreccio Readi, Catterina; Pruyas, Martha; Lagos Lucero, Marcela; Van De Wyngard, Vanessa; Poggi, Helena; Cook, María Paz; Viviani, Paola; Barriga, María I.; Ferreccio Readi, Catterina; Pruyas, MarthaAbstract Background We previously conducted a population-based screening trial of high-risk human papillomavirus (hrHPV) testing and conventional cytology, demonstrating higher sensitivity (92.7 % vs 22.1 % for CIN2+) but lower positive predictive value (10.5 % vs 23.9 %) of hrHPV testing. Here we report the performance of HPV16/18 genotyping to triage the hrHPV positive participants. Methods Women aged 25 years and older received hrHPV (Hybrid Capture 2) and Papanicolaou testing; positives by either test underwent colposcopy and directed biopsy, as did a sample of double-negatives. hrHPV positive women were reflex-tested with HPV16/18 genotyping (Digene HPV Genotyping PS Test). Results Among the 8,265 participants, 10.7 % were hrHPV positive, 1.7 % had ASCUS+ cytology, 1.2 % had CIN2+; 776 (88 %) hrHPV positive women had complete results, of whom 38.8 % were positive for HPV16 (24.0 %), HPV18 (9.7 %) or both (5.1 %). CIN2+ prevalence in HPV16/18 positive women (16.3 %, 95 % CI 12.3-20.9) was twice that of HPV16/18 negative women (8.0 %, 95 % CI 5.7-10.8). HPV16/18 genotyping identified 40.5 % of CIN2, 66.7 % of CIN3 and 75.0 % of cancers. Compared to hrHPV screening alone, HPV16/18 triage significantly reduced the referral rate (10.7 % vs 3.7 %) and the number of colposcopies required to detect one CIN2+ (9 vs 6). When HPV16/18 negative women with baseline ASCUS+ cytology were also colposcopied, an additional 14 % of CIN2+ was identified; referral increased slightly to 4.2 %. Conclusions HPV16/18 triage effectively stratified hrHPV positive women by their risk of high-grade lesions. HPV16/18 positive women must be referred immediately; referral could be deferred in HPV16/18 negative women given the slower progression of non-HPV16/18 lesions, however, they will require active follow-up.Abstract Background We previously conducted a population-based screening trial of high-risk human papillomavirus (hrHPV) testing and conventional cytology, demonstrating higher sensitivity (92.7 % vs 22.1 % for CIN2+) but lower positive predictive value (10.5 % vs 23.9 %) of hrHPV testing. Here we report the performance of HPV16/18 genotyping to triage the hrHPV positive participants. Methods Women aged 25 years and older received hrHPV (Hybrid Capture 2) and Papanicolaou testing; positives by either test underwent colposcopy and directed biopsy, as did a sample of double-negatives. hrHPV positive women were reflex-tested with HPV16/18 genotyping (Digene HPV Genotyping PS Test). Results Among the 8,265 participants, 10.7 % were hrHPV positive, 1.7 % had ASCUS+ cytology, 1.2 % had CIN2+; 776 (88 %) hrHPV positive women had complete results, of whom 38.8 % were positive for HPV16 (24.0 %), HPV18 (9.7 %) or both (5.1 %). CIN2+ prevalence in HPV16/18 positive women (16.3 %, 95 % CI 12.3-20.9) was twice that of HPV16/18 negative women (8.0 %, 95 % CI 5.7-10.8). HPV16/18 genotyping identified 40.5 % of CIN2, 66.7 % of CIN3 and 75.0 % of cancers. Compared to hrHPV screening alone, HPV16/18 triage significantly reduced the referral rate (10.7 % vs 3.7 %) and the number of colposcopies required to detect one CIN2+ (9 vs 6). When HPV16/18 negative women with baseline ASCUS+ cytology were also colposcopied, an additional 14 % of CIN2+ was identified; referral increased slightly to 4.2 %. Conclusions HPV16/18 triage effectively stratified hrHPV positive women by their risk of high-grade lesions. HPV16/18 positive women must be referred immediately; referral could be deferred in HPV16/18 negative women given the slower progression of non-HPV16/18 lesions, however, they will require active follow-up.
- ItemRegional variations in Helicobacter pylori infection, gastric atrophy and gastric cancer risk : The ENIGMA study in Chile(2020) Herrero, R.; Heise, K.; Acevedo, J.; Cook, María Paz; Gonzalez, C.; Gahona, J.; Cortes, R.; Collado, L.; Beltran, M. E.; Ferreccio Readi, Catterina; Cikutovic, M.; Gonzalez, P.; Murillo, R.; Leja, M.; Megraud, F.; Hernandez, M. D.; Barbier, S.; Park, J. Y.
- ItemSalmonella enterica serovar Typhi and gallbladder cancer : a case control study and meta-analysis(2016) Koshiol, Jill; Wozniak Banchero, Aniela; Cook, María Paz; Adaniel, Christina; Acevedo, Johanna; Azócar, Lorena; Roa Strauch, Juan Carlos Enrique; Miquel P., Juan Francisco; Ferreccio Readi, Catterina; Díaz, Alfonso; Molina, Héctor; Miranda, Carolina; Castillo, Claudia