Browsing by Author "Cruz, A"

Now showing 1 - 3 of 3
  • Thumbnail Image
    Item
    Determination of a BRCA1 gene mutation in a family with hereditary breast cancer
    (SOC MEDICA SANTIAGO, 2004) Gallardo, M; Faundez, P; Cruz, A; Rodriguez, M; Alvarez, M; Carvallo, P
    Background: Breast cancer is the main cause of death among fore, the women between 40 and 55 years old, in whom the hereditary cases are common. Therefore molecular diagnosis of germ line initiations involved in breast cancer susceptibilily is relevant. BRCA1 and BRCA2 have been described as the two major genes involved in familial breast/ovarian cancer. We are performing a screening for BRCA 1 and BRCA2 genes, in a group of 50 high risk Chilean families for breast/ovarian cancer. We have detected a mutation, 3936 C > T, that leads to a truncated protein, in two affected women from one of the families in study.
  • Thumbnail Image
    Item
    Use of quillaja saponins (Quillaja saponaria Molina) to control acid mist in copper electrowinning processes - Part 1. Laboratory scale evaluation
    (ELSEVIER SCIENCE BV, 2005) San Martin, RM; Otero, AF; Figueroa, M; Escobar, V; Cruz, A
    This work describes the use of extracts of the Chilean quillaja tree (Quillaja saponaria Molina) as alternative low cost surfactants for the control of acid mist in copper electrowinning (EW). Quillaja extracts contain triterpenoid saponins, which are natural surfactants traditionally used as foaming agents in food and beverages. Two commercial products with different degrees of purification were tested: QL 1000 (R) (non-refined product, 8.4% saponin content) and Mistop (R) (refined product, 16% saponin content). Laboratory experiments determined the effects of both products on electrolyte surface tension (ST), solvent extraction process (SX), current efficiency (CE) and cathode quality.
  • Thumbnail Image
    Item
    Use of quillaja saponins (Quillaja saponaria Molina) to control acid mist in copper electrowinning processes - Part 2: Pilot plant and industrial scale evaluation
    (ELSEVIER SCIENCE BV, 2005) San Martin, RM; Otero, AF; Cruz, A
    This work describes the use of Mistop (R), a novel surfactant of natural origin that contains primarily triterpenoid saponins (active ingredient), to control acid mist in copper electrowinning (EW). Previous laboratory tests indicated that Mistop (R) has no negative effects on cathode quality, current efficiency, and overall solvent extraction (SX) process conditions (e.g. phase disengagement time, extraction/stripping kinetics, maximum charge/discharge, etc.).