Browsing by Author "Espinoza, Claudia"

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    Perfil clínico-epidemiológico de las infecciones por virus respiratorios en adultos hospitalizados durante la estación de influenza 2004
    (2006) Rabagliati, Ricardo; Serri, Michel; Perret Perez, Cecilia; Guzmán Durán, Ana María; Azócar, Teresa; Habash, Leila; Espinoza, Claudia; Ferrés Garrido, Marcela Viviana
    Background: During yearly influenza (FLU) season, FLU viruses are well represented among hospitalized patients as in the community. Also, other respiratory viruses could be represented among adult in-patients. Aim: to describe the presence and clinical- epidemiological characteristics of non-FLU respiratory virus infections (respiratory syncytial-RSV, parainfluenza and adenovirus-ADV) among hospitalized adults during FLU season and to compare with FLU-A (IA) or -B (IB) cases. Patients and Methods: Adult patients hospitalized at Hospital Clínico Universidad Católica between May to July 2004 with a respiratory virus infections confirmed by rapid antigen test or direct immunofluorescence of IA, IB (Flu group) or RSV, parainfluenza (1-2-3) and ADV (non-Flu group) were included. Results: 86 cases were identified: 73.5% FLU (48.2% IA, 25.3% IB) and 26.5% non-FLU (15.7% parainfluenza-2; 8.4% RSV; 1.2% parainfluenza-3; 1.2% ADV). No differences were observed in general characteristics and evolution of patients. In FLU-group were more frequently observed myalgia, cough, hospitalization due to febrile syndrome, higher values of C-reactive protein and band leukocytes count (p < 0.05). Conclusions: During 2004 FLU season a 26.5 % of respiratory viral infection were due to non-FLU viruses among adult hospitalized in our centre. The difficulty to difference FLU vs. non-FLU infections, suggest that it is necessary to include other respiratory virus in the viral etiological diagnosis, even in FLU season.
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    Utilidad de una encuesta para identificar donantes de sangre de zonas no endémicas, potencialmente infectados con Trypanosoma cruzi
    (1999) Vásques, Marcela; Vidal, Sylvia; Espinoza, Claudia; Palomo, Iván; Torres, Marisa; Alvarado, Christian; Canales, Marinela; Salinas, Ana María; Pereira, Jaime; Jerez, Guillermo
    Large numbers of immigrants from endemic areas for Chagas' disease resided in Maule Region and transmission can occur by blood transfusion.is important evaluated the usefulness of a questionnaire for identifying Trypanosoma cruzi infected blood donors in nonendemic area. In this work participate blood donors of 7 hospitals of the Region. During the 6-month period, 1.581 blood donors were asked and their samples were analysed for T. cruzi antibodies.The effectiveness of the questionnaire was evaluated by comparing donor's answers about their risk for Chagas' disease with the result of testing with an enzyme-linked immunosorbent assay. Positives samples were confirm by: indirect immunofluorescence, and polymerase chain reaction. Only one donor was positive to Chagas' disease. This donors reported no risk factors. Therefore blood donors seropositive for T. cruzi are presente in donors population of nonendemic area without the usual identifiable risk factors.