Browsing by Author "Fabres, Jorge"
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- ItemEnteral Feeding and Necrotizing Enterocolitis: Does Time of First Feeds and Rate of Advancement Matter?(LIPPINCOTT WILLIAMS & WILKINS, 2021) Masoli, Daniela; Domínguez De Landa, María Angélica; Tapia, Jose L.; Uauy, Ricardo; Fabres, Jorge; NEOCOSUR Collaborative NetworkThe aim of the study was to determine if time to initial enteral feeding (EF) and rate of advancement are associated with necrotizing enterocolitis (NEC) or death. Methods: Secondary analysis of prospectively collected data of very-low-birth-weight infants (VLBWI: 400--1500 g) born in 26 NEOCOSUR centers between 2000 and 2014. Results: Among 12,387 VLBWI, 83.7% survived without NEC, 6.6% developed NEC and survived, and 9.6% had NEC and died or died without NEC (NEC/death). After risk adjustment, time to initial EF (median = 2 days) was not associated with NEC; however, delaying it was protective for NEC/death (odds ratio [OR] = 0.96; 95% confidence interval [CI] 0.93--0.99). A slower feeding advancement rate (FAR) was protective for NEC (OR = 0.97; 95% CI = 0.94-0.98) and for NEC/death (OR = 0.98; 95% CI = 0.96-0.99). Conclusions: In VLBWI, there was no association between an early initial EF and NEC, although delaying it was associated with less NEC/death. A slower FAR was associated with lower risk of both outcomes.
- ItemPaCO2 and Neurodevelopment in Extremely Low Birth Weight Infants(MOSBY-ELSEVIER, 2009) McKee, Lara A.; Fabres, Jorge; Howard, George; Peralta Carcelen, Myriam; Carlo, Waldemar A.; Ambalavanan, NamasivayamObjective To determine the relationship between PaCO2 in the first 4 days of life and neurodevelopment at 18 to 22 months.
- ItemRandomized Trial of Early Bubble Continuous Positive Airway Pressure for Very Low Birth Weight Infants(MOSBY-ELSEVIER, 2012) Tapia, Jose L.; Urzua, Soledad; Bancalari, Aldo; Meritano, Javier; Torres, Gabriela; Fabres, Jorge; Toro, Claudia A.; Rivera, Fabiola; Cespedes, Elizabeth; Burgos, Jaime F.; Mariani, Gonzalo; Roldan, Liliana; Silvera, Fernando; Gonzalez, Agustina; Dominguez, Angelica; S Amer Neocosur NetworkObjective To determine whether very low birth weight infants (VLBWIs), initially supported with continuous positive airway pressure (CPAP) and then selectively treated with the INSURE (intubation, surfactant, and extubation to CPAP; CPAP/INSURE) protocol, need less mechanical ventilation than those supported with supplemental oxygen, surfactant, and mechanical ventilation if required (Oxygen/mechanical ventilation [MV]).
- ItemResults of Extremely-low-birth-weight Infants Randomized to Receive Extra Enteral Calcium Supply(LIPPINCOTT WILLIAMS & WILKINS, 2011) Carroll, William F.; Fabres, Jorge; Nagy, Tim R.; Frazier, Marcela; Roane, Claire; Pohlandt, Frank; Carlo, Waldemar A.; Thome, Ulrich H.Background and Objective: Bone mineral deficiency continues to occur in extremely-low-birth-weight (ELBW) infants despite formulas enriched in calcium (Ca) and phosphorus (P). This study tested whether extra enteral Ca supplementation increases bone mineral content (BMC) and prevents dolichocephalic head flattening and myopia in ELBW infants.