Browsing by Author "Ferres, M"

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    Dengue-1 virus isolation during first dengue fever outbreak on Easter Island, Chile
    (CENTER DISEASE CONTROL, 2003) Perret, C; Abarca, K; Ovalle, J; Ferrer, P; Godoy, P; Olea, A; Aguilera, X; Ferres, M
    Dengue virus was detected for the first time in Chile, in an outbreak of dengue fever on Easter Island. The virus was isolated in tissue culture and characterized by reverse transcription-polymerase chain reaction as being dengue type 1.
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    Neutralizing antibodies in survivors of Sin Nombre and Andes hantavirus infection
    (CENTERS DISEASE CONTROL, 2006) Valdivieso, F; Vial, P; Ferres, M; Ye, CY; Goade, D; Cuiza, A; Hjelle, B
    We evaluated titers of homotypic and heterotypic neutralizing antibodies (NAbs) to Andes and Sin Nombre hantaviruses in plasma samples from 20 patients from Chile and the United States. All but 1 patient had high titers of NAb. None of the plasma samples showed high titers against the heterologous virus.
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    Prevalence of Epstein Barr virus infection in healthy individuals in Santiago, Chile
    (SOC MEDICA SANTIAGO, 1995) Ferres, M; Prado, P; Ovalle, J; Fuentes, R; Villarroel, L; Ferreccio, C; Vial, P
    To study the rate of infection by Epstein Barr virus (EBV) in Santiago, Chile, the prevalence of antibody to the viral capsid antigen (VCA-lgG) was determined in a group of 663 healthy individuals grouped by age and socioeconomic level (SEL). In addition, several risk factors for infection were studied. VCA-lgG was determined by ELISA. The total prevalence was 76,7%. When grouped by age and SEL, 50% of the children from low and medium SEL had been already infected by the age two, compared to 5,9% in the high SEL (p<0.01). However, by age twenty, 90% of the total sample had already specific antibodies to EBV. Age and number of household members were positively associated with the infection. High socioeconomic level represented a delay factor in the acquisition of the virus, (p<0.01). These results show that EBV infection is frequent in Santiago, occurring early in childhood among medium and low SEL. Hence, the classical infectious mononucleosis should be recognized more frequently among adolescents and young adults belonging to high SEL, while the clinical spectrum of associated manifestations different from the typical mononucleosis syndrome should be investigated among these exposed in early age.