Browsing by Author "Gatica, MA"

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    AChE-rich magnopyramidal neurons have a left-right size asymmetry in Broca's area
    (ELSEVIER SCIENCE BV, 2004) Garcia, RR; Montiel, JF; Villalon, AU; Gatica, MA; Aboitiz, F
    Acetylcholinesterase-rich neurons (AChERN) are a particular group of pyramidal neurons, displaying a specific laminar and ontogenetic pattern in the cerebral cortex of human and nonhuman primates. Using histochemistry and morphometrical methods, we have found a layer 3 magnopyramidal AChERN left-right size asymmetry restricted to Brodmann's area 45, a component of Broca's language area. This structural feature could be related to functional lateralization associated to syntactic processing and phonological working memory, and is consistent with a non-cholinergic role of AChE possibly linked to neuroplastic processes in the human neocortex. (C) 2004 Elsevier B.V. All rights reserved.