Browsing by Author "Gonzalez, Francisco G."

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    S-Nitrosation of β-Catenin and p120 Catenin A Novel Regulatory Mechanism in Endothelial Hyperpermeability
    (2012) Marin, Natalie; Zamorano, Patricia; Carrasco, Rodrigo; Mujica, Patricio; Gonzalez, Francisco G.; Quezada, Claudia; Meininger, Cynthia J.; Boric, Mauricio P.; Duran, Walter N.; Sanchez, Fabiola A.
    Rationale: Endothelial adherens junction proteins constitute an important element in the control of microvascular permeability. Platelet-activating factor (PAF) increases permeability to macromolecules via translocation of endothelial nitric oxide synthase (eNOS) to cytosol and stimulation of eNOS-derived nitric oxide signaling cascade. The mechanisms by which nitric oxide signaling regulates permeability at adherens junctions are still incompletely understood.