Browsing by Author "Gonzalez, Hernan E."
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- ItemAltered Chemokine Receptor Expression in Papillary Thyroid Cancer(MARY ANN LIEBERT, INC, 2009) Gonzalez, Hernan E.; Leiva, Andrea; Tobar, Hugo; Boehmwald, Karen; Tapia, Grace; Torres, Javiera; Mosso, Lorena M.; Bueno, Susan M.; Gonzalez, Pablo; Kalergis, Alexis M.; Riedel, Claudia A.Background: Papillary thyroid cancer (PTC), the most prevalent type of differentiated thyroid carcinoma, displays a strikingly high frequency of lymph node metastasis (LNM). Recent data suggest that chemokines can play an important role in promoting tumor progression and metastatic migration of tumor cells. Here we have evaluated whether PTC tissues express a different pattern of chemokine receptors and if the expression of these receptors correlates with LNM.
- ItemDifferential expression profile of CXCR3 splicing variants is associated with thyroid neoplasia. Potential role in papillary thyroid carcinoma oncogenesis?(2018) Urra, Soledad; Fischer, Martin C.; Martinez, Jose R.; Veliz, Loreto; Orellana, Paulina; Solar González, Antonieta Alejandra; Bohmwald Prieto, Karen; Kalergis Parra, Alexis Mikes; Riedel, Claudia; Corvalán R., Alejandro; Roa Strauch, Juan Carlos Enrique; Fuentealba, Rodrigo; Cáceres, C. Joaquín; López Lastra, Marcelo Andrés; León Ramírez, Augusto; Droppelmann, Nicolás; Gonzalez, Hernan E.
- ItemRadioactive Iodine Administration Is Associated with Persistent Related Symptoms in Patients with Differentiated Thyroid Cancer(2016) Florenzano Valdés, Pablo Felipe; Guarda Vega, Francisco; Jaimovich, Rodrigo; Droppelmann, Nicolás; Gonzalez, Hernan E.; Domínguez Ruiz-Tagle, José Miguel
- ItemStudy and management of thyroid nodes by non specialist physicians: SOCHED consensus(SOC MEDICA SANTIAGO, 2017) Tala, Hernan; Diaz, Rene E.; Dominguez Ruiz Tagle, Jose Miguel; Sapunar Zenteno, Jorge; Pineda, Pedro; Arroyo Albala, Patricia; Barberan, Marcela; Cabane, Patricio; Cruz Olivos, Francisco; Patricio Gac, E.; Glasinovic Pizarro, Andrea; Gonzalez, Hernan E.; Grob, Francisca; Hidalgo Valle, Maria Soledad; Jaimovich, Rodrigo; Lanas, Alejandra; Liberman, Claudio; Lobo Guinez, Maite; Madrid, Arturo; Moreno Seguel, Marcela; Mosso, Lorena; Fernando Munizaga, C.; Ortiz Parada, Eugenia; Osorio Gonnet, Fernando; Slater Morales, Jeannie; Solar, Antonieta; Stehr, Carlos; Vasquez Rodriguez, Felix; Veliz, Jesus; Villaseca Najarian, Roberto; Wohllk, NelsonThe thyroid nodule is a frequent cause of primary care consultation. The prevalence of a palpable thyroid nodule is approximately 4-7%, increasing up to 67% by the incidental detection of nodules on ultrasound. The vast majority are benign and asymptomatic, staying stable over time. The clinical importance of studying a thyroid nodule is to exclude thyroid cancer, which occurs in 5 to 10% of the nodules. The Board of SOCHED (Chilean Society of Endocrinology and Diabetes) asked the Thyroid Study Group to develop a consensus regarding the diagnostic management of the thyroid nodule in Chile, aimed at non-specialist physicians and adapted to the national reality. To this end, a multidisciplinary group of 31 experts was established among university academics, active researchers with publications on the subject and prominent members of scientific societies of endocrinology, head and neck surgery, pathology and radiology. A total of 14 questions were developed with key aspects for the diagnosis and subsequent referral of patients with thyroid nodules, which were addressed by the participants. In those areas where the evidence was insufficient or the national reality had to be considered, the consensus opinion of the experts was used through the Delphi methodology. The consensus was approved by the SOCHED board for publication.