Browsing by Author "Gyawali, Smita"
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- ItemGalectin-8 Promotes Cytoskeletal Rearrangement in Trabecular Meshwork Cells through Activation of Rho Signaling(PUBLIC LIBRARY SCIENCE, 2012) Diskin, Shiri; Chen, Wei Sheng; Cao, Zhiyi; Gyawali, Smita; Gong, Haiyan; Soza, Andrea; Gonzalez, Alfonso; Panjwani, NoorjahanPurpose: The trabecular meshwork (TM) cell-matrix interactions and factors that influence Rho signaling in TM cells are thought to play a pivotal role in the regulation of aqueous outflow. The current study was designed to evaluate the role of a carbohydrate-binding protein, galectin-8 (Gal8), in TM cell adhesion and Rho signaling.