Browsing by Author "Hurtado, Daniel"

Now showing 1 - 2 of 2
  • No Thumbnail Available
    Item
    Comprehensive Assessment of Left Intraventricular Hemodynamics Using a Finite Element Method: An Application to Dilated Cardiomyopathy Patients
    (2021) Franco, Pamela; Sotelo, Julio; Montalba, Cristian; Ruijsink, Bram; Kerfoot, Eric; Nordsletten, David; Mura, Joaquin; Hurtado, Daniel; Uribe, Sergio
    In this paper, we applied a method for quantifying several left intraventricular hemodynamic parameters from 4D Flow data and its application in a proof-of-concept study in dilated cardiomyopathy (DCM) patients. In total, 12 healthy volunteers and 13 DCM patients under treatment underwent short-axis cine b-SSFP and 4D Flow MRI. Following 3D segmentation of the left ventricular (LV) cavity and registration of both sequences, several hemodynamic parameters were calculated at peak systole, e-wave, and end-diastole using a finite element approach. Sensitivity, inter- and intra-observer reproducibility of hemodynamic parameters were evaluated by analyzing LV segmentation. A local analysis was performed by dividing the LV cavity into 16 regions. We found significant differences between volunteers and patients in velocity, vorticity, viscous dissipation, energy loss, and kinetic energy at peak systole and e-wave. Furthermore, although five patients showed a recovered ejection fraction after treatment, their hemodynamic parameters remained low. We obtained several hemodynamic parameters with high inter- and intra-observer reproducibility. The sensitivity study revealed that hemodynamic parameters showed a higher accuracy when the segmentation underestimates the LV volumes. Our approach was able to identify abnormal flow patterns in DCM patients compared to volunteers and can be applied to any other cardiovascular diseases.
  • No Thumbnail Available
    Item
    Dilatation and shearing in tectono-volcanic systems from poro-elasto-plastic models set in the Southern Andes Volcanic Zone context, inferences on geofluid flow
    (2022) Gerbault, Muriel; Saez, Felipe; Ruz Ginouves, Javiera; Cembrano, José; Iturrieta, Pablo; Hurtado, Daniel; Hassani, Riad; Browning, John
    Geothermal fields near volcanic complexes and active crustal-scale fault zones require an understanding of the mechanical interactions that control variations in pore fluid pressure at a crustal scale. Crustal faults can trigger and modify fluid flow depending mostly on their geometry and mechanical properties. In turn, fluid flow reduces normal stresses causing either shearing or dilation through the rock mass, concomitant with hydraulic fracturing or seismic fault reactivation. The Southern Andes Volcanic Zone (SAVZ) documents widespread geofluid migration through the crust within a bulk regional transpressive regime. We address here the key role of dilatational domains potentially hosting geothermal fluids, in close relation to shear zones, by using elasto-plastic and poro-elasto-plastic models. First we define models considering Drucker-Prager elasto-plasticity, that account for either: 1) an inflating magmatic cavity or 2) a dextral slipping fault zone ca. 4 km apart, to assess the rheological conditions leading to brittle failure of the bedrock around the fault zone and the cavity, respectively. This setup is applied to the San-Pedro Tatara volcanic complex in the SAVZ. Parametric tests of Young’s moduli and frictional strength provide not only the conditions for macro-scale shear failure, but also shows the development of diffuse domains of dilatational strain in the intervening bedrock. Both void opening and/or volumetric cracking may lead to an increase in porosity and/or permeability, allowing over-pressurized geofluids to migrate within these domains. Our results (Ruz Ginouves et al., JVGR, 2021) show that generally, shallow magma chambers (~< 4 km) and fault zones must be close enough to trigger bedrock failure of the other counterpart (< 4 km), unless the magma chamber is deeper than 10 km, the magma overpressure is high or the regional strength is very low. We argue that alternating strike-slip faulting and magmatic overpressure promote a variety of stress fields that may explain observations of transient fluid pathways on seemingly independent timescales along the Andean margin. To gain further insights into these processes, we develop a numerical scheme to quantify stress and fluid flow with a coupled poro-mechanical approach implemented using Python’s Opensource FEM library FeniCS. Benchmarks are first presented to validate our poro-elasto-plastic approach. Then a synthetic setup shows how fluids get channelized around a fault zone several days after an imposed fault slip motion. Preliminary results are discussed in comparison to a high enthalpy geothermal system associated with another volcanic complex in the SAVZ.