Browsing by Author "Kogan Alterman, Marcelo"
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- ItemA New Kind of Quinonic-Antibiotic Useful Against Multidrug-Resistant S. aureus and E. faecium Infections(2018) Campanini Salinas, Javier; Andrades Lagos, Juan; González Rocha, Gerardo; Choquesillo Lazarte, Duane; Bollo Dragnic, Soledad; Faúndez Cáceres, Mario; Alarcón, Pedro; Silva, Francisco; Vidal, Roberto; Salas Huenuleo, Edison; Kogan Alterman, Marcelo; Mella, Jaime; Recabarren Gajardo, Gonzalo; Vásquez Velásquez, David
- ItemBiology and management of Cuscuta in crops.(2005) Kogan Alterman, Marcelo; Lanini, W. T.
- ItemDinámica de los residuos de insecticidas durante el proceso de elaboración de deshidratados de manzanas y ciruelas(2016) Alister Herdener, Claudio Andrés; Becerra, B. Kevin; Araya, Manuel; Kogan Alterman, Marcelo; Volosky, Christian
- ItemEffects of physicochemical soil properties of five agricultural soils on herbicide soil adsorption and leaching.(2011) Alister Herdener, Claudio Andrés.; Araya, Manuel.; Kogan Alterman, Marcelo
- ItemGold nanoparticles stabilized with beta cyclodextrin-2-amino-4-(4-chlorophenyl)thiazole complex: a novel system for drug transport(2017) Kogan Alterman, Marcelo; Yutronic, N.; Sierpe, R.; Vásquez, D.; Campanini, J.; Andrades, J.; Simon, U.; Noyong, M.; Asela, I.
- ItemNanoparticle-Mediated Angiotensin-(1-9) Drug Delivery for the Treatment of Cardiac Hypertrophy(2021) Sepúlveda-Rivas, Sabrina; Leal, Matías S.; Pedrozo, Zully; Kogan Alterman, Marcelo; Ocaranza Jeraldino, María Paz; Morales, JavierAng-(1-9) peptide is a bioactive vasodilator peptide that prevents cardiomyocyte hypertrophy in vitro and in vivo as well as lowers blood pressure and pathological cardiovascular remodeling; however, it has a reduced half-life in circulation, requiring a suitable carrier for its delivery. In this work, hybrid nanoparticles composed of polymeric nanoparticles (pNPs) based on Eudragit® E/Alginate (EE/Alg), and gold nanospheres (AuNS), were developed to evaluate their encapsulation capacity and release of Ang-(1-9) under different experimental conditions. Hybrid pNPs were characterized by dynamic light scattering, zeta potential, transmission and scanning electron microscopy, size distribution, and concentration by nanoparticle tracking analysis. Nanometric pNPs, with good polydispersity index and colloidally stable, produced high association efficiency of Ang-(1-9) and controlled release. Finally, the treatment of neonatal cardiomyocytes in culture with EE/Alg/AuNS 2% + Ang-(1-9) 20% pNPs decreased the area and perimeter, demonstrating efficacy in preventing norepinephrine-induced cardiomyocyte hypertrophy. On the other hand, the incorporation of AuNS did not cause negative effects either on the cytotoxicity or on the association capacity of Ang-(1-9), suggesting that the hybrid carrier EE/Alg/AuNS pNPs could be used for the delivery of Ang-(1-9) in the treatment of cardiovascular hypertrophy.
- ItemPersistencia de la actividad en el suelo de flazasulfuron aplicado después del transplante del tomate.(2002) Kogan Alterman, Marcelo
- ItemUsing penoxsulam ALS inhibitor as a broad - spectrum herbicide in Chilean rice.(2011) Kogan Alterman, Marcelo; Gómez, Patricio; Fischer, Albert; Alister Herdener, Claudio Andrés
- ItemUso de adyuvantes para disminuir el efecto del lavado del glifosato desde el follaje de Cyperus rotundus L..(2001) Kogan Alterman, Marcelo
- ItemWeed control intensity effects on young radiata pine growth. Crop Protection 21:253-257(2002) Kogan Alterman, Marcelo; Figueroa Espinoza, Rorigo; Gilabert P., Horacio