Browsing by Author "Kramer, Veronica"
Now showing 1 - 3 of 3
Results Per Page
Sort Options
- ItemCardiovascular risk factors in a group of health care workers(SOC MEDICA SANTIAGO, 2012) Kramer, Veronica; Adasme, Marcela; Jose Bustamante, M.; Jalil, Jorge; Navarrete, Carlos; Acevedo, MonicaBackground: Health promotion can be carried out at work places. Aim: To assess cardiovascular risk factors among workers of a University hospital. Material and Methods: Cross sectional study of 888 participants (aged 41 +/- 11 years, 76% women), who answered a survey about cardiovascular risk factors. Body mass index, waist, blood pressure and total cholesterol (TC) by capillary method were determined. Results: Self reported prevalence of risk factors were as follows: 19% of participants had high blood pressure, 30% hypercholesterolemia, 6% diabetes, 41% smoked, 88% were sedentary and 26% had a family history of cardiovascular diseases. Five percent of participants did not have any risk factor, 20% had one risk factor, 32% had two and 43% had three or more. The highest frequency of lack of awareness was about blood glucose values. A high blood cholesterol level was found in 27% of those reporting normal cholesterol levels. Likewise, a high body mass index was found in 18% of those reporting a normal weight. Conclusions: The prevalence of cardiovascular risk factors in this group of participants is similar to that found in the last national health survey in Chile. Noteworthy is the lack of awareness about these risk factors. (Rev Med Chile 2012; 140: 602-608).
- ItemComparison of Lipoprotein-Associated Phospholipase A2 and High Sensitive C-Reactive Protein as Determinants of Metabolic Syndrome in Subjects without Coronary Heart Disease: In Search of the Best Predictor(HINDAWI LTD, 2015) Acevedo, Monica; Varleta, Paola; Kramer, Veronica; Valentino, Giovanna; Quiroga, Teresa; Prieto, Carolina; Parada, Jacqueline; Adasme, Marcela; Briones, Luisa; Navarrete, CarlosHigh sensitivity C-reactive protein (hsCRP) is a marker of metabolic syndrome (MS) and cardiovascular (CV) disease. Lipoproteinassociated phospholipase A2 (Lp-PLA2) also predicts CV disease. There are no reports comparing these markers as predictors of MS. Methods. Cross-sectional study comparing Lp-PLA2 and hsCRP as predictors of MS in asymptomatic subjects was carried out; 152 subjects without known atherosclerosis participated. Data were collected on demographics, cardiovascular risk factors, anthropometric and biochemical measurements, and hsCRP and Lp-PLA2 activity levels. A logistic regression analysis was performed with each biomarker and receiver operating characteristic (ROC) curves were constructed for MS. Results. Mean age was 46 +/- 11 years, and 38% of the subjects had MS. Mean Lp-PLA2 activity was 185 +/- 48 nmol/mL/min, and mean hsCRP was 2.1 +/- 2.2mg/L. Subjects with MS had significantly higher levels of Lp-PLA2 (P = 0.03) and hsCRP (P < 0.0001) than those without MS. ROC curves showed that both markers predictedMS. Conclusion. Lp-PLA2 and hsCRP are elevated in subjects withMS. Both biomarkers were independent and significant predictors for MS, emphasizing the role of inflammation in MS. Further research is necessary to determine if inflammation predicts a higher risk for CV events in MS subjects.
- ItemHipertensión arterial: el factor de riesgo más importante para grosor íntima-media carotídeo elevado y placa carotídea en adultos de Santiago(SOC MEDICA SANTIAGO, 2011) Acevedo, Monica; Tagle, Rodrigo; Kramer, Veronica; Arnaiz, Pilar; Marin, Arnaldo; Pino, Felipe; Godoy, Ivan; Berrios, Ximena; Navarrete, CarlosBackground: Carotid Ultima media thickness (CIMT) is a marker of cardiovascular damage that can be modified by traditional risk factors. Aim: To determine attributable risk factors for a high CIMT among healthy adults. Material and Methods: A sample of 1270 individuals (636 males and 634 females) aged 44 +/- 11 years, was studied. Blood pressure, weight, height, lipid profile and blood glucose were measured in all. CIMT and the presence of atherosclerotic plaques were determined by carotid ultrasound. Standard criteria were used to define hypertension, dyslipidemia and diabetes. Results: Mean CIMT in the sample studied was 0.62 +/- 0.01 mm and percentile 75 was 0.67. The most important risk factor for a CIMT over percentile 75 and the presence of atherosclerotic plaques was hypertension with attributable risks of 54 and 57%, respectively. Conclusions: In this sample, the main risk factor for a high CIMT was hypertension. (Rev Med Chile 2011; 139: 290-297).