Browsing by Author "Maiz, Alberto"

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    A possible association between primary aldosteronism and a lower beta-cell function
    (LIPPINCOTT WILLIAMS & WILKINS, 2007) Mosso, Lorena M.; Carvajal, Cristian A.; Maiz, Alberto; Ortiz, Eugenia H.; Castillo, Carmen R.; Artigas, Rocio A.; Fardella, Carlos E.
    Objective Primary aldosteronism ( PA) is the most common secondary cause of hypertension and recently has been implicated as a cause of impaired glucose tolerance. We investigated the glucose insulin sensitivity and insulin secretion in patients with idiopathic primary aldosteronism.
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    Allelic Variants of Melanocortin 3 Receptor Gene (MC3R) and Weight Loss in Obesity: A Randomised Trial of Hypo-Energetic High- versus Low-Fat Diets
    (PUBLIC LIBRARY SCIENCE, 2011) Santos, Jose L.; De la Cruz, Rolando; Holst, Claus; Grau, Katrine; Naranjo, Carolina; Maiz, Alberto; Astrup, Arne; Saris, Wim H. M.; MacDonald, Ian; Oppert, Jean Michel; Hansen, Torben; Pedersen, Oluf; Sorensen, Thorkild I. A.; Alfredo Martinez, J.; NUGENOB Consortium
    Introduction: The melanocortin system plays an important role in energy homeostasis. Mice genetically deficient in the melanocortin-3 receptor gene have a normal body weight with increased body fat, mild hypophagia compared to wild-type mice. In humans, Thr6Lys and Val81Ile variants of the melanocortin-3 receptor gene (MC3R) have been associated with childhood obesity, higher BMI Z-score and elevated body fat percentage compared to non-carriers. The aim of this study is to assess the association in adults between allelic variants of MC3R with weight loss induced by energy-restricted diets.
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    Disfuncionalidad antioxidante de las lipoproteínas de alta densidad (HDL) en pacientes diabéticos descompensados
    (2015) Awad, Fernanda; Contreras Duarte, Susana de las Mercedes; Molina, Patricia; Quiñones, Verónica; Serrano, V.; Abbott Cáceres, Eduardo Francisco; Maiz, Alberto; Busso, Dolores; Rigotti Rivera, Attilio
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    Influence of obesity on health care costs and absenteeism among employees of a mining company
    (SOC MEDICA SANTIAGO, 2009) Zarate, Aldo; Crestto, Marco; Maiz, Alberto; Ravest, Gonzalo; Ines Pino, Maria; Valdivia, Gonzalo; Moreno, Manuel; Villarroel, Luis
    Background: The health associated costs of obesity can represent obesity on health care costs and absenteeism in a cohort of mine workers. Patients and methods: Prospective study of 4.673 of men, employees of a mining company, aged 49 +/- 7 years that were followed for 24 +/- 11 months. Total health care costs and days of sick leave were recorded for each individual. The association between obesity and these variables and analyzed by logistic regression adjusting for co-morbidities, age and other variables. Results: Mean annual health care cots for obese workers were 17% higher (p<0.001) compared to workers with normal weight and 58% higher (p<0.001) for workers with severe and morbid obesity. Mean annual days of sick leave increased by 25% in the obese (p=0.002) and by 57% in subjects with severe and morbid obesity (p<0.001). For health care costs the most significant predictors were: presence of diabetes mellitus (Odds ratio (OR) 6.21, 95% confidence intervals (95% CI) 4.9 to 7.9), hypertension (OR 3.99; 95% CI 3.4 to 4.6) and severe and morbid obesity (OR 2.55, 95% CI 1.9 to 3.4). For absenteeism the most significant predictors were; presence of diabetes mellitus (OR 1.58, 95% CI 1.2 to 2.0), hypertension (OR 1.34, 95% CI 1.2 to 1.6) and severe and morbid obesity (OR 1.50, 95% CI 1.1 to 2.1). Conclusions: Obesity increases significantly health care costs and absenteeism (Rev Med Chile 2009; 137: 337-44).
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    Medical and Surgical Treatments for Obesity Have Opposite Effects on Peptide YY and Appetite: A Prospective Study Controlled for Weight Loss
    (ENDOCRINE SOC, 2010) Valderas, Juan P.; Irribarra, Veronica; Boza, Camilo; de la Cruz, Rolando; Liberona, Yessica; Maria Acosta, Ana; Yolito, Macarena; Maiz, Alberto
    Context: The effects of medical and surgical treatments for obesity on peptide YY (PYY) levels, in patients with similar weight loss, remain unclear.
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    Second Consensus of the Chilean Society of Endocrinology and Diabetes about insulin resistance
    (SOC MEDICA SANTIAGO, 2015) Pollak, Felipe; Araya, Veronica; Lanas, Alejandra; Sapunar, Jorge; Arrese, Marco; Gloria Aylwin, Carmen; Gloria Bezanilla, Carmen; Carrasco, Elena; Carrasco, Fernando; Codner, Ethel; Diaz, Erik; Durruty, Pilar; Galgani, Jose; Garcia, Hernan; Lahsen, Rodolfo; Liberman, Claudio; Lopez, Gloria; Maiz, Alberto; Mujica, Veronica; Poniachik, Jaime; Sir, Teresa; Soto, Nestor; Valderas, Juan; Villaseca, Paulina; Zavala, Carlos
    Insulin resistance is a prevalent condition commonly associated with unhealthy lifestyles. It affects several metabolic pathways, increasing risk of abnormalities at different organ levels. Thus, diverse medical specialties should be involved in its diagnosis and treatment. With the purpose of unifying criteria about this condition, a scientific-based consensus was elaborated. A questionnaire including the most important topics such as cardio-metabolic risk, non-alcoholic fatty liver disease and polycystic ovary syndrome, was designed and sent to national experts. When no agreement among them was achieved, the Delphi methodology was applied. The main conclusions reached are that clinical findings are critical for the diagnosis of insulin resistance, not being necessary blood testing. Acquisition of a healthy lifestyle is the most important therapeutic tool. Insulin-sensitizing drugs should be prescribed to individuals at high risk of disease according to clinically validated outcomes. There are specific recommendations for pregnant women, children, adolescents and older people.