Browsing by Author "Mc Nab, P"

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    Effects of Carvedilol upon intra- and interventricular synchrony in patients with chronic heart failure
    (EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC, 2005) Castro, PF; Mc Nab, P; Quintana, JC; Bittner, A; Greig, D; Vergara, I; Vukasovic, JL; Corbalan, R; Copaja, M; Diaz Araya, G; Chiong, M; Troncoso, R; Alcaino, H; Lavandero, S
    Radionuclide isotopic ventriculography with phase analysis was performed in 30 patients with stable heart failure (HF), determining left ventricular (LV) and interventricular contraction synchrony at baseline and after 6 months of treatment with maximal tolerated doses of carvedilol. Patients with HF had significant ventricular dyssynchrony compared with a normal population. The 50th percentile of patients with the greatest dyssynchrony at baseline showed significant improvement in ventricular synchrony after receiving carvedilol, and this was correlated positively with a reduction in end-diastolic LV volumes. (c) 2005 Elsevier Inc. All rights reserved.