Browsing by Author "Medina, L."

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    Breast cancer and pregnancy: A comparative analysis of a Chilean cohort
    (2014) Sánchez, C.; Acevedo Claros, Francisco Nicolás; Medina, L.; Ibáñez, C.; Razmilic Valdés, Dravna Nichi; Navarro Ortega, María Elena; Camus, M.
    Introduction: Recent reports show that pregnancy-associated breast cancer (PABC) survival is similar to that of non-pregnant young patients. We evaluate the characteristics and prognosis of PABC patients treated in our cancer centre. Patients and methods: We identified patients with invasive PABC who were treated between 1999 and May 2013 and compared their characteristics with a no PABC cohort of similar age. Results: The prevalence of PABC was 1% (n = 17). The median age was 35 years (range: 29– 42 years). The initial tumour was suspected clinically in 93% of the cases. Total mastectomy rates were higher in women with PABC (78.6% versus 40.5%, p = 0.02), and more tumours in the PABC group were triple negative, epidermal growth factor type 2 (HER2)–positive, and at advanced stages; however, these differences were not statistically significant. While estimated overall survival at ten years was higher in the non-PABC group (75.5% versus 80.5%, p = 0.043), disease-specific survival (DSS) rate at ten years was not statistically different between groups (83.9% for PABC and 75.5% for unrelated pregnancy BC, p = 0.37). Conclusions: PABC is a rare event. In our cohort, it tended to be more aggressive. Compared with a similar age cohort, the DSS was not worse.
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    High prevalence of vitamin D deficiency in women with breast cancer : The first Chilean study
    (2016) Acevedo Claros, Francisco Nicolás; Pérez, V.; Pérez Sepúlveda, A.; Florenzano Valdés, Pablo Felipe; Artigas, R.; Medina, L.; Sanchez, Cesar G.