Browsing by Author "Ortiz, Carolina"

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    Benefits of home-based administration of palivizumab in high-risk groups
    (2024) Ortiz, Carolina; Vasquez, Ignacia; Zamorano, Alejandra; D'Apremont, Ivonne; Pittaluga, Enrica; Diaz, Marcela; Campos, Catalina
    Palivizumab, a humanized monoclonal antibody against the respiratory syncytial virus (RSV), rrently is indicated in groups at higher risk of developing severe RSV disease, such as extreme premature infants and patients with hemodynamically significant heart disease. In Chile, this strategy guaranteed by Law 20850 (Ricarte Soto Law). Nevertheless, barriers to its administration included the need to transfer these labile patients and exposure to other users, with the risk of contagion waiting rooms. Objective: to describe the impact of the palivizumab administration strategy in home care program for high-risk patients. Patients and Method: retrospective, descriptive, observational cohort study of patients born before 32 weeks of gestation or weighing less than 1500 grams, who received palivizumab between January 2019 and December 2021 at the Hospital Dr. S & oacute;tero Rio. . Results: 272 patients were included (median gestational age: 30 weeks). The percentage of doses administered at home was 35.9% (2019) and 37.2% (2021). Each dose of 2020 following the administration in Neonatology, was administered at home during the COVID-19 pandemic. The median interval between doses was as recommended. Adherence was over 90%. The unadjusted incidence RSV infection was 5.7% (2019), 0% (2020), and 0.9% (2021). Conclusions: palivizumab administration was adequate and timely; home indication was associated with high adherence rates and administration interval between doses in line with current recommendations.
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    Improvement in adherence to Mediterranean diet in children attending preschool centers
    (2024) Jobet, Emilia; Loyola, Maria Ines; Ortiz, Carolina; Rigotti, Attilio; Echeverria, Guadalupe; Mallea, Claudia; Barja, Salesa
    Background: the Mediterranean diet has been associated with a lower prevalence of obesity and metabolic syndrome, and with healthier lifestyles in adults and children, but data is scarce in younger ages. The Mediterranean -type ecosystem of the central region of Chile as well as its traditional gastronomy would facilitate the adoption of this dietary pattern. Objectives: to assess the adherence to Mediterranean diet in preschoolers and their parents, and to evaluate the impact of a nutrition education intervention and diet implementation. Methods: prospective cohort study. The KidMed index was applied to children older than 18 months, and the Mediterranean Dietary Index in Chile (Chilean-MDI) to their parents, before and after a remote educational intervention. Results: one hundred and thirty-nine families participated, with 95 preschoolers; 56 % were girls, aged 26.2 +/- 8.7 months. The basal mean KidMed score was 7.4 +/- 1.9 and increased to 7.9 +/- 1.9 after the intervention (p = 0.1). The Chilean-MDI score was 6.9 +/- 1.8 and 7.1 +/- 1.7, respectively (p = 0.09). When separated by categories, there was improvement from low and moderate adherence to optimal adherence in both children and their parents (Chi2, p = 0.009 y p = 0.04). In 58 dyads, there was a positive correlation between the KidMed and the Chilean-MDI index, pre- and post -intervention (Pearson R = 0.3 y 0.34; p = 0.004 y 0.003, respectively). Conclusions: most of these sample of preschoolers and their parents had a moderate adherence to Mediterranean diet, with an improvement after an educational intervention.
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    Successful unilateral vasectomy reversal in a lion (Panthera leo)
    (2019) Marconi, Marcelo; de la Torre, Jose Manuel; Palma, Cristian; Gallegos, Hector; Soto, Evelyn; Celis, Sebastian; de la Torre, Camila; Ortiz, Carolina; Duarte, Alberto; Idalsoaga, Ignacio
    Background: In 2016, the veterinarian team of Buin Zoo in Chile decided to try to increase the lion population. At that time, the zoo had three lions; two females and one male. The 9-year-old male had been vasectomized 5 years ago at the same institution for birth control. Considering the fact that in humans, vasectomy reversal has excellent reproductive outcomes, a team of human urologists, highly experienced in vasectomy reversal was contacted to perform the procedure.