Browsing by Author "Pablo Cruz, Juan"

Now showing 1 - 3 of 3
  • No Thumbnail Available
    Item
    Circumflex Scapular Artery Pseudoaneurysm as an Unusual Source of Emboli in Recurrent Posterior Circulation Stroke
    (2022) Marine, Leopoldo; Velasquez, Fernando; Sandoval, Patricio; Mellado, Patricio; Carlos Zamora, Juan; Vergara, Francisco; Pablo Cruz, Juan
    Objective: To present a rare cause of recurrent posterior embolic strokes originating from a partially thrombosed pseudoaneurysm of a shoulder artery after arthroscopy. Materials and Methods: The clinical history, complementary studies and follow-up were reviewed. Results: The patient was successfully embolized and presented no new ischemic episodes at the 3-month follow-up visit. Conclusions: Shoulder artery pseudoaneurysm should be considered as an unusual source of posterior embolic strokes.
  • Thumbnail Image
    Item
    Functional Dysconnectivity in Ventral Striatocortical Systems in 22q11.2 Deletion Syndrome
    (OXFORD UNIV PRESS, 2021) Tepper, Angeles; Cuiza Vasquez Analia; Alliende, Luz María; Mena, Carlos; Ramirez Mahaluf, Juan Pablo; Iruretagoyena, Barbara; Ornstein, Claudia; Fritsch, Rosemarie; Nachar, Ruben; Gonzalez Valderrama, Alfonso; Undurraga, Juan; Pablo Cruz, Juan; Tejos, Cristian; Fornito, Alex; Repetto, Gabriela; Crossley, Nicolas
    22q11.2 deletion syndrome (22q11.2DS) is a genetic neurodevelopmental disorder that represents one of the greatest known risk factors for psychosis. Previous studies in psychotic subjects without the deletion have identified a dopaminergic dysfunction in striatal regions, and dysconnectivity of striatocortical systems, as an important mechanism in the emergence of psychosis. Here, we used resting-state functional MRI to examine striatocortical functional connectivity in 22q11.2DS patients. We used a 2 x 2 factorial design including 125 subjects (55 healthy controls, 28 22q11.2DS patients without a history of psychosis, 10 22q11.2DS patients with a history of psychosis, and 32 subjects with a history of psychosis without the deletion), allowing us to identify network effects related to the deletion and to the presence of psychosis. In line with previous results from psychotic patients without 22q11.2DS, we found that there was a dorsal to ventral gradient of hypo- to hyperstriatocortical connectivity related to psychosis across both patient groups. The 22q11.2DS was additionally associated with abnormal functional connectivity in ventral striatocortical networks, with no significant differences identified in the dorsal system. Abnormalities in the ventral striatocortical system observed in these individuals with high genetic risk to psychosis may thus reflect a marker of illness risk.
  • No Thumbnail Available
    Item
    Portal biliopathy: a multitechnique imaging approach
    (2012) Besa, Cecilia; Pablo Cruz, Juan; Huete, Alvaro; Cruz, Francisco
    Portal biliopathy (PB) is a disorder characterized by biliary ductal and gallbladder wall abnormalities seen in patients with extrahepatic portal vein obstruction. These abnormalities consist mainly of bile duct compression and tethering, stenoses, fibrotic strictures and dilatation of both extrahepatic and intrahepatic bile ducts, as well as gallbladder varices. In this pictorial essay, we describe the imaging findings of PB, which allow differentiation of this entity from other diseases that may have similar imaging findings including cholangiocarcinoma, extrinsic compression of the bile duct caused by metastatic adenopathy or sclerosing cholangitis.