Browsing by Author "Parada, J."
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- ItemCopy number polymorphism of the salivary amylase gene: Implications in human nutrition research(2012) Santos Martín, José Luis; Saus, E.; Smalley Meylan, Susan Valerie; Cataldo Bascuñan, Luis Rodrigo; Alberti Reus, Gigliola Loredana; Parada, J.; Gratacòs, M.; Estivill, X.The salivary alpha-amylase is a calcium-binding enzyme that initiates starch digestion in the oral cavity. The alpha-amylase genes are located in a cluster on the chromosome that includes salivary amylase genes (AMY1), two pancreatic alpha-amylase genes (AMY2A and AMY2B) and a related pseudogene. The AMY1 genes show extensive copy number variation which is directly proportional to the salivary alpha-amylase content in saliva. The alpha-amylase amount in saliva is also influenced by other factors, such as hydration status, psychosocial stress level, and short-term dietary habits. It has been shown that the average copy number of AMY1 gene is higher in populations that evolved under high-starch diets versus low-starch diets, reflecting an intense positive selection imposed by diet on amylase copy number during evolution. In this context, a number of different aspects can be considered in evaluating the possible impact of copy number variation of the AMY1 gene on nutrition research, such as issues related to human diet gene evolution, action on starch digestion, effect on glycemic response after starch consumption, modulation of the action of alpha-amylases inhibitors, effect on taste perception and satiety, influence on psychosocial stress and relation to oral health. Copyright (C) 2012 S. Karger AG, Basel
- ItemCortisol y amilasa salival en niñas: variación según la curva diurna, la ingesta de alimentos y la actividad física. Diurnal variation of salivary cortisol and α amylase levels in normal girls. Effects of meals and physical exercise(2015) Araya, S.; Cataldo Bascuñan, Luis Rodrigo; Calderon, C.; Weisstaub, G.; Parada, J.; Hodgson Bunster, María Isabel; Santos Martín, José Luis
- ItemDesign of low glycemic response foods using polyphenols from seaweed(2019) Parada, J.; Perez Correa, Jose Ricardo; Pérez-Jiménez, J.
- ItemDevelopment of alginate microspheres containing thyme essential oil using ionic gelation(2016) Benavides, S.; Cortés, P.; Parada, J.; Franco, Wendy
- ItemInteractions between Starch, Lipids, and Proteins in Foods : Microstructure Control for Glycemic Response Modulation(2016) Parada, J.; Santos Martín, José Luis
- ItemLeptin/Adiponectin Ratios Using Either Total Or High-Molecular-Weight Adiponectin as Biomarkers of Systemic Insulin Sensitivity in Normoglycemic Women(2017) Bravo, C.; Cataldo Bascuñan, Luis Rodrigo; Galgani Fuentes, José; Parada, J.; Santos Martín, José Luis