Browsing by Author "Peña, Marcela"
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- ItemCognitive and Neural Effects of a Brief Nonsymbolic Approximate Arithmetic Training in Healthy First Grade Children(2018) Gouet, Camilo; Gutierrez Silva, Cesar A.; Guedes, Bruno; Peña, Marcela
- ItemEducating to Build Bridges(2013) Goldin, Andrea Paula; Calero, Cecilia Inés; Peña, Marcela; Ribeiro, Sidarta; Sigman, Mariano
- ItemEffect of feeding mode on infant growth and cognitive function: study protocol of the Chilean infant Nutrition randomized controlled Trial (ChiNuT)(2020) Toro Campos, Rosario.; Peña, Marcela; Uauy, Ricardo; Algarín, Cecilia.; Peirano, Patricio.; Murguia-Peniche, Teresa.; Wu, Steven S.Abstract Background A central aim for pediatric nutrition is to develop infant formula compositionally closer to human milk. Milk fat globule membranes (MFGM) have shown to have functional components that are found in human milk, suggesting that addition of bovine sources of MFGM (bMFGM) to infant formula may promote beneficial outcomes potentially helping to narrow the gap between infants who receive human breast milk or infant formula. The objective of the current study is to determine how the addition of bMFGM in infant formula and consumption in early infancy affects physical growth and brain development when compared to infants fed with a standard formula and a reference group of infants fed with mother’s own milk. Methods Single center, double-blind, and parallel randomized controlled trial. Planned participant enrollment includes: infants exclusively receiving breast milk (n = 200; human milk reference group; HM) and infants whose mothers chose to initiate exclusive infant formula feeding before 4 months of age (n = 340). The latter were randomized to receive one of two study formulas until 12 months of age: 1) cow’s milk based infant formula that had docosahexaenoic (DHA) (17 mg/100 kcal) and arachidonic acid (ARA) (25 mg/100 kcal); 1.9 g protein/100 kcal; 1.2 mg Fe/100 kcal (Standard formula; SF) or 2) a similar infant formula with an added source of bovine MFGM (whey protein-lipid concentrate (Experimental formula; EF). Primary outcomes will be: 1) Physical growth (Body weight, length, and head circumference) at 730 days of age; and 2) Cognitive development (Auditory Event-Related Potential) at 730 days of age. Data will be analyzed for all participants allocated to each study feeding group. Discussion The results of this study will complement the knowledge regarding addition of bMFGM in infant formula including support of healthy growth and improvement of neurodevelopmental outcomes. Trial registration NCT02626143, registered on December 10th 2015.Abstract Background A central aim for pediatric nutrition is to develop infant formula compositionally closer to human milk. Milk fat globule membranes (MFGM) have shown to have functional components that are found in human milk, suggesting that addition of bovine sources of MFGM (bMFGM) to infant formula may promote beneficial outcomes potentially helping to narrow the gap between infants who receive human breast milk or infant formula. The objective of the current study is to determine how the addition of bMFGM in infant formula and consumption in early infancy affects physical growth and brain development when compared to infants fed with a standard formula and a reference group of infants fed with mother’s own milk. Methods Single center, double-blind, and parallel randomized controlled trial. Planned participant enrollment includes: infants exclusively receiving breast milk (n = 200; human milk reference group; HM) and infants whose mothers chose to initiate exclusive infant formula feeding before 4 months of age (n = 340). The latter were randomized to receive one of two study formulas until 12 months of age: 1) cow’s milk based infant formula that had docosahexaenoic (DHA) (17 mg/100 kcal) and arachidonic acid (ARA) (25 mg/100 kcal); 1.9 g protein/100 kcal; 1.2 mg Fe/100 kcal (Standard formula; SF) or 2) a similar infant formula with an added source of bovine MFGM (whey protein-lipid concentrate (Experimental formula; EF). Primary outcomes will be: 1) Physical growth (Body weight, length, and head circumference) at 730 days of age; and 2) Cognitive development (Auditory Event-Related Potential) at 730 days of age. Data will be analyzed for all participants allocated to each study feeding group. Discussion The results of this study will complement the knowledge regarding addition of bMFGM in infant formula including support of healthy growth and improvement of neurodevelopmental outcomes. Trial registration NCT02626143, registered on December 10th 2015.
- ItemElectrophysiological evidence of statistical learning of long-distance dependencies in 8-month-old preterm and full-term infants(2015) Kabdebon, C.; Peña, Marcela; Buiatti, M.; Dehaene-Lambertz, G.
- ItemExecutive attention impairment in first-episode schizophrenia(2012) Peña, Marcela; Orellana, Gricel.; Slachevsky, Andrea.Abstract Background We compared the attention abilities of a group of first-episode schizophrenia (FES) patients and a group of healthy participants using the Attention Network Test (ANT), a standard procedure that estimates the functional state of three neural networks controlling the efficiency of three different attentional behaviors, i.e., alerting (achieving and maintaining a state of high sensitivity to incoming stimuli), orienting (ability to select information from sensory input), and executive attention (mechanisms for resolving conflict among thoughts, feelings, and actions). Methods We evaluated 22 FES patients from 17 to 29 years of age with a recent history of a single psychotic episode treated only with atypical neuroleptics, and 20 healthy persons matched with FES patients by sex, age, and educational level as the control group. Attention was estimated using the ANT in which participants indicate whether a central horizontal arrow is pointing to the left or the right. The central arrow may be preceded by spatial or temporal cues denoting where and when the arrow will appear, and may be flanked by other arrows (hereafter, flankers) pointing in the same or the opposite direction. Results The efficiency of the alerting, orienting, and executive networks was estimated by measuring how reaction time was influenced by congruency between temporal, spatial, and flanker cues. We found that the control group only demonstrated significantly greater attention efficiency than FES patients in the executive attention network. Conclusions FES patients are impaired in executive attention but not in alerting or orienting attention, suggesting that executive attention deficit may be a primary impairment during the progression of the disease.Abstract Background We compared the attention abilities of a group of first-episode schizophrenia (FES) patients and a group of healthy participants using the Attention Network Test (ANT), a standard procedure that estimates the functional state of three neural networks controlling the efficiency of three different attentional behaviors, i.e., alerting (achieving and maintaining a state of high sensitivity to incoming stimuli), orienting (ability to select information from sensory input), and executive attention (mechanisms for resolving conflict among thoughts, feelings, and actions). Methods We evaluated 22 FES patients from 17 to 29 years of age with a recent history of a single psychotic episode treated only with atypical neuroleptics, and 20 healthy persons matched with FES patients by sex, age, and educational level as the control group. Attention was estimated using the ANT in which participants indicate whether a central horizontal arrow is pointing to the left or the right. The central arrow may be preceded by spatial or temporal cues denoting where and when the arrow will appear, and may be flanked by other arrows (hereafter, flankers) pointing in the same or the opposite direction. Results The efficiency of the alerting, orienting, and executive networks was estimated by measuring how reaction time was influenced by congruency between temporal, spatial, and flanker cues. We found that the control group only demonstrated significantly greater attention efficiency than FES patients in the executive attention network. Conclusions FES patients are impaired in executive attention but not in alerting or orienting attention, suggesting that executive attention deficit may be a primary impairment during the progression of the disease.Abstract Background We compared the attention abilities of a group of first-episode schizophrenia (FES) patients and a group of healthy participants using the Attention Network Test (ANT), a standard procedure that estimates the functional state of three neural networks controlling the efficiency of three different attentional behaviors, i.e., alerting (achieving and maintaining a state of high sensitivity to incoming stimuli), orienting (ability to select information from sensory input), and executive attention (mechanisms for resolving conflict among thoughts, feelings, and actions). Methods We evaluated 22 FES patients from 17 to 29 years of age with a recent history of a single psychotic episode treated only with atypical neuroleptics, and 20 healthy persons matched with FES patients by sex, age, and educational level as the control group. Attention was estimated using the ANT in which participants indicate whether a central horizontal arrow is pointing to the left or the right. The central arrow may be preceded by spatial or temporal cues denoting where and when the arrow will appear, and may be flanked by other arrows (hereafter, flankers) pointing in the same or the opposite direction. Results The efficiency of the alerting, orienting, and executive networks was estimated by measuring how reaction time was influenced by congruency between temporal, spatial, and flanker cues. We found that the control group only demonstrated significantly greater attention efficiency than FES patients in the executive attention network. Conclusions FES patients are impaired in executive attention but not in alerting or orienting attention, suggesting that executive attention deficit may be a primary impairment during the progression of the disease.
- ItemGaze Following Is Accelerated in Healthy Preterm Infants(2014) Peña, Marcela; Arias Ernst, Diana Patricia; Dehaene-Lambertz, G.
- ItemListening Natively Across Perceptual Domains?(2016) Langus, A.; Seyed, S.; Uysal, E.; Pirmoradian, S.; Marino, C.; Asaadi, S.; Eren, O.; Toro, J.; Peña, Marcela; Bion, R.; Nespor, M.
- ItemMother-Infant Face-to-Face Interaction : The Communcative Value of Infant-Directed Talking and Singing(2016) Arias Ernst, Diana Patricia; Peña, Marcela
- ItemNeuroscience and education: prime time to build the bridge(2014) Sigman, M.; Peña, Marcela; Goldi, Andrea; Ribeiro, Sidarta
- ItemPotenciales consecuencias neurocognitivas de infección por virus respiratorio sincicial humano(2016) Flores, Juan Carlos; Bohmwald Prieto, Karen; Espinoza Véliz, Janyra Alejandra; Jara, Cristina; Peña, Marcela; Hoyos Bachiloglu, Rodrigo Andrés; Iturriaga, Carolina; Kalergis Parra, Alexis Mikes; Borzutzky Schachter, Arturo
- ItemReading Comprehension in Latin America : difficulties and Possible Interventions(2016) Lions, Séverin.; Peña, Marcela
- ItemRhythm on Your Lips(2016) Peña, Marcela; Langus, Alan; Gutiérrez, César; Huepe Artigas, Daniela; Nespor, Marina
- ItemSevere respiratory disease caused by human respiratory syncytial virus impairs language learning during early infancy(2020) Peña, Marcela; Jara González, María Cristina; Flores, Juan Carlos; Hoyos Bachiloglu, Rodrigo Andrés; Medina Lainez, Mariana Andrea; Carcey Rivera, Javier Ignacio; Espinoza Véliz, Janyra Alejandra; Bohmwald Prieto, Karen; Kalergis Parra, Alexis Mikes; Borzutzky Schachter, Arturo; Iturriaga, C.
- ItemYoung infants can learn object and action-words from continuous audiovisual streams(2018) Jara González, María Cristina; Peña, Marcela; Pontificia Universidad Católica de Chile. Escuela de PsicologíaTesis (Doctor en Psicología)--Pontificia Universidad Católica de Chile, 2018