Browsing by Author "Perez, O"

Now showing 1 - 3 of 3
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    Effects of carvedilol on oxidative stress and chronotropic response to exercise in patients with chronic heart failure
    (WILEY, 2005) Castro, P; Vukasovic, JL; Chiong, M; Diaz Araya, G; Alcaino, H; Copaja, M; Valenzuela, R; Greig, D; Perez, O; Corbalan, R; Lavandero, S
    Background: Our previous studies suggest that the increase in heart rate from rest to peak exercise is reduced in patients with chronic heart failure (CHF) and this is associated with increased oxidative stress, as determined by malondialdehyde (MDA) plasma levels.
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    Effects of early decrease in oxidative stress after medical therapy in patients with class IV congestive heart failure
    (EXCERPTA MEDICA INC, 2002) Castro, PF; Diaz Araya, G; Nettle, D; Corbalan, R; Perez, O; Nazzal, C; Larrain, G; Lavandero, S
    It has been reported that patients with congestive heart failure (CHF) have increased breath pentane content, conjugated diene levels, and plasma malondialdehyde (MDA) levels, an indirect marker of lipid peroxidation.(1-3) Ghatak et al(4) found that patients with chronic CHF had increased MDA and superoxide levels, which correlated with the severity of the CHF. Low glutathione levels and superoxide dismutase (SOD) activity have also been reported.(5,6) There have been no studies in human refractory CHF to evaluate the impact of acute intensive medical therapy on oxidative stress status and antioxidant enzyme activity. We determined the plasma levels of MDA, SOD, catalase (CAT), and glutathione peroxidase (GSH-Px) activities before and after therapeutic intervention in patients with chronic advanced CHF and refractory symptoms (New York Heart Association functional class IV).
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    Effects of glucose-insulin-potassium solution on myocardial salvage and left ventricular function after primary angioplasty
    (LIPPINCOTT WILLIAMS & WILKINS, 2003) Castro, PF; Larrain, G; Baeza, R; Corbalan, R; Nazzal, C; Greig, DP; Miranda, FP; Perez, O; Acevedo, M; Marchant, E; Olea, E; Gonzalez, R
    Objective. To evaluate the effects of glucose-insulin-potassium (GIK) therapy on infarct size and left ventricular function when used as an adjuvant therapy to primary angioplasty.