Browsing by Author "Pizarro, Guadalupe del C."

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    Copolymeric hydrogels with high capacities of hydration and methylene blue adsorption in water
    (2024) Oyarce, Estefania; Diaz, Hector; Boulett, Andres; Roa, Karina; Sanchez, Julio; Marambio, Oscar G.; Pizarro, Guadalupe del C.
    Copolymers based on monomethyl hydrogen itaconate (beta HI) with 2-hydroxyethyl methacrylate (HEMA) and beta HI with 2-hydroxypropyl methacrylate (HPMA) were prepared in different monomer molar ratios. The reactivity parameters of copolymerization (r1 and r2) were determined. The values obtained for r1 and r2 indicate that P (beta HI-co-HEMA) exhibits a high tendency towards alternate copolymerization. Structural characterization of the copolymeric hydrogels was carried out using Fourier transform infrared (FTIR) and 1H NMR spectroscopies, where the characteristic signals of the constituent functional groups were observed. The typical thermal stability of the polymeric systems was observed by thermogravimetric analysis (TGA). In addition, the swelling capacity in water was evaluated, and a swelling percentage over 655 % and 1249 % presented P(beta HI-co-HEMA) and P (beta HI-co-HPMA) respectively, in a period of 15 days at pH 10, and presence of 0.05 M NaNO3. Additionally, methylene blue (MB) adsorption capacity was studied in batch mode by varying different experimental parameters. MB adsorption capacity of 122.79 mg g- 1 and 112.24 mg g- 1 were achieved for P(beta HIco-HEMA) and P(beta HI-co-HPMA), respectively. The data obtained were fitted to the Elovich kinetic model and to a Redlich-Peterson isotherm. The thermodynamic parameters indicated that the adsorption phenomenon is spontaneous, endothermic and with a high probability of occurrence. The adsorption efficiency decreases by approximately 60 % in the presence of interfering ions (Na+, K+, Ca2+ and Cl-). The adsorbents are reusable and achieve high MB adsorption efficiency (90 % and 80 % for P(beta HI-co-HEMA) and P(beta HI-co-HPMA) respectively) in a textile-simulated wastewater. Based on the results obtained, it is concluded that P(beta HI-co-HEMA) and P(beta HI-coHPMA) show great potential for use in adsorption of water molecules, for MB retention and purification of simulated effluents from the textile industry.
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    From Concentrated Dispersion to Solid beta-Cyclodextrin Polymer-Capped Silver Nanoparticle Formulation: A Trojan Horse Against Escherichia coli
    (2019) Martin Trasanco, Rudy; Anziani Ostuni, Giovanna; Esparza Ponce, Hilda Esperanza; Ortiz Rodríguez, Pedro David; Montero Cabrera, María E.; Oyarzún, Diego P.; Zúñiga, César; Pérez Donoso, José Manuel; Pizarro, Guadalupe del C.; Arratia Pérez, Ramiro
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    In-Situ Preparation of CdTe Quantum Dots Capped with beta-Cyclodextrin-Epichlorohydrin Polymer : Polymer Influence on the Nanocrystal's Optical Properties
    (2018) Martin-Trasanco, Rudy; Esparza-Ponce, Hilda E.; Ortiz Rodríguez, Pedro David; Oyarzun, Diego P.; Zuniga, Cesar; Montero-Cabrera, Maria E.; Tundidor Camba, Alain; Pizarro, Guadalupe del C.; Arratia-Perez, Ramiro
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    Nanoreactors based on self-Assembled amphiphilic diblock copolymers for the preparation of ZnO nanoparticles
    (2013) Pizarro, Guadalupe del C.; Marambio, Oscar G.; González Enríquez, Carmen; Sarabia-Vallejos, Mauricio A.; Geckeler, Kurt E.
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    Polycaprolactone and poly-β-cyclodextrin polymer blend: a Biopolymers composite film for drug release
    (2022) Antonella Sepulveda, Francesca; Sanchez, Julio; Oyarzun, Diego P.; Rodriguez-Gonzalez, Fidel E.; Tundidor-Camba, Alain; Garcia-Herrera, Claudio; Zapata, Paula A.; Pizarro, Guadalupe del C.; Martin-Trasanco, Rudy
    Nowadays, biomedical films containing drug carriers are preferred over conventional ones, since the protection of the injury and the therapy is joined within a single device. In the current work, we prepared polycaprolactone (PCL) composite films with beta-cyclodextrin (beta CD) or its epichlorohydrin crosslinked polymer (beta CDP) as ibuprofen (Ibu) drug carrier. The composite films were prepared at different PCL/additive ratios (2, 5, 10 and 20 wt%). ATR-FTIR spectroscopy and water contact angle (WCA) measurements indicated a scarce presence of the additives on the surface. Cross-section scanning electron micrographs showed the presence of aggregates corresponding to beta CD and beta CDP in the inner regions of the films. The incorporation of beta CD and beta CDP into the PCL films did not affect their thermal properties as was determined from differential scanning calorimetry (DSC). PCL-films with 10 wt% of the inclusion complexes Ibu@beta CD and Ibu@beta CDP were prepared and the release studies were performed. At pH = 7.2, PCL-Ibu@beta CDP composite film released 55% of Ibu within the first six hours; eight times the amount released by PCL-Ibu@beta CD within the same time interval. A plausible mechanism for ibuprofen release is discussed based on the cross-section SEM micrographs of composite films.