Browsing by Author "Poblete, MI"
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- ItemClonidine-induced nitric oxide-dependent vasorelaxation mediated by endothelial α2-adrenoceptor activation(2001) Figueroa, XF; Poblete, MI; Boric, MP; Mendizábal, VE; Adler-Graschinsky, E; Huidobro-Toro, JP1 To assess the involvement of endothelial alpha (2)-adrenoceptors in the clonidine-induced vasodilatation, the mesenteric artery of Sprague Dawley rats was cannulated and perfused with Tyrode solution (2 ml min(-1)). We measured perfusion pressure, nitric oxide (NO) in the perfusate using chemiluminescence, and tissue cyclic GMP by RIA.