Browsing by Author "Saez, T."
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- ItemCross-sectional and longitudinal lipid determination studies in pregnant women reveal an association between increased maternal LDL cholesterol concentrations and reduced human umbilical vein relaxation(2015) Leiva Mendoza, Andrea Alejandra; Salsoso Rodríguez, M. Rocío; Saez, T.; Sanhueza, C.; Pardo, F.; Sobrevía Luarte, Luis Alberto
- ItemFetoplacental endothelial dysfunction in maternal hypercholesterolemia and obesity in pregnancy(2014) Pardo, F.; Silva Lagos, Luis Alfredo; Salsoso Rodríguez, M. Rocío; Saez, T.; Farías Jofré, Marcelo Enrique; Villalobos Labra, Roberto Esteban; Leiva Mendoza, Andrea Alejandra; Sanhueza, C.; Sobrevía Luarte, Luis Alberto
- ItemIncreased placental angiogenesis in late and early onset pre-eclampsia is associated with differential activation of vascular endothelial growth factor receptor 2(W B SAUNDERS CO LTD, 2014) Escudero, C.; Celis, C.; Saez, T.; San Martin, S.; Valenzuela, F. J.; Aguayo, C.; Bertoglia, P.; Roberts, J. M.; Acurio, J.Introduction: Placentas from both early-onset (EOPE) and late-onset pre-eclampsia (LOPE) exhibit signs of underperfusion, which in turn, may be associated with altered angiogenesis. Tyrosine 951 (Y951) and Y1175 phosphorylation of the vascular endothelial growth factor receptor 2 (VEGFR2) induced by VEGF triggers the angiogenesis process. Endothelial markers such as CD31 and CD34 have been used for estimating angiogenic processes in several tissues, including placenta. We asked whether vascular density in placental villi was related to Y951/Y1175 phosphorylation of VEGFR2 in LOPE or EOPE.
- ItemInsulin receptor isoforms: an integrated view focused on gestational diabetes mellitus(2016) Westermeier, F.; Saez, T.; Arroyo, P.; Toledo, F.; Gutierrez, J.; Sanhueza, C; Pardo, F.; Leiva Mendoza, Andrea Alejandra; Sobrevía Luarte, Luis Alberto
- ItemInsulin restores L-arginine transport requiring adenosine receptors activation in umbilical vein endothelium from late-onset preeclampsia(2015) Salsoso Rodríguez, M. Rocío; Guzman, E.; Saez, T.; Bugueno, K.; Ramirez, M.; Farías Jofré, Marcelo Enrique; Pardo, F.; Leiva Mendoza, Andrea Alejandra; Sanhueza, C.; Mate, A.; Vazquez, C.; Sobrevía Luarte, Luis Alberto
- ItemInsulin Reverses D-Glucose-Increased Nitric Oxide and Reactive Oxygen Species Generation in Human Umbilical Vein Endothelial Cells(2015) Gonzalez, M.; Rojas, S.; Avila. P.; Cabrera, L.; Villalobos Labra, Roberto Esteban; Palma, C.; Aguayo, C.; Pena, E.; Salsoso Rodríguez, M. Rocío; Leiva Mendoza, Andrea Alejandra; Sobrevía Luarte, Luis Alberto; Gallardo, V.; Guzman-Gutierrez, E.; Saez, T.; Sanhueza, C.; Pardo, F.
- ItemInsulin therapy and fetoplacental vascular function in gestational diabetes mellitus(2015) Sobrevía Luarte, Luis Alberto; Salsoso Rodríguez, M. Rocío; Saez, T.; Pardo, F.; Leiva Mendoza, Andrea Alejandra; Sanhueza, C.
- ItemInsulin/adenosine axis linked signalling(2017) Silva Lagos, Luis Alfredo; Subiabre Morales, Mario Enrique; Araos, J.; Saez, T.; Salsoso Rodríguez, M. Rocío; Pardo, F.; Leiva Mendoza, Andrea Alejandra; San Martin, R.; Toledo, F.; Sobrevía Luarte, Luis Alberto
- ItemIntracellular and extracellular pH dynamics in the human placenta from diabetes mellitus(2016) Araos, J.; Silva, L.; Salsoso Rodríguez, M. Rocío; Saez, T.; Barros Lamus, Eric Raúl; Toledo, F.; Gutierrez, J.; Pardo, F.; Leiva Mendoza, Andrea Alejandra; Sanhueza C.; Sobrevía Luarte, Luis Alberto
- ItemMaternal hypercholesterolemia in pregnancy associates with umbilical vein endothelial dysfunction : role of endothelial nitric oxide synthase and arginase II(2013) Leiva Mendoza, Andrea Alejandra; Salsoso Rodríguez, M. Rocío; Saez, T.; San Martín, S.; Abarzúa C., Fernando; Farías Jofré, Marcelo Enrique; Pardo, F.; Sobrevía Luarte, Luis Alberto
- ItemNitric Oxide is a Central Common Metabolite in Vascular Dysfunction Associated with Diseases of Human Pregnancy(2016) Leiva Mendoza, Andrea Alejandra; Fuenzalida Saavedra, Bárbara; Barros Lamus, Eric Raúl; Sobrevia, B.; Salsoso Rodríguez, M. Rocío; Saez, T.; Villalobos Labra, Roberto Esteban; Silva Lagos, Luis Alfredo; Chiarello, I.; Toledo, F.; Gutierrez, J.; Sanhueza, C.; Pardo, F.; Sobrevía Luarte, Luis Alberto