Browsing by Author "Salas, Patricio"

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    Analyzing the Determinants of Teleworking during the COVID-19 Pandemic in Chile
    (2024) Astroza, Sebastian; Hurtubia, Ricardo; Tirachini, Alejandro; Guevara, C. Angelo; Carrasco, Juan Antonio; Salas, Patricio; Munizaga, Marcela
    The COVID-19 pandemic triggered an unprecedented increase in telework, a trend expected to have lasting effects on the labor market and commuting patterns, including location preferences. Understanding the demand for telework is critical to face the challenges that may come in present and future scenarios with hybrid work arrangements. In this paper, a model for the probability of telework is proposed and estimated with data collected during two different periods of the COVID-19 pandemic, in 2020, in Chile. The model measures the correlation between several socioeconomic characteristics, and latent variables related to concerns about health and the economy, with the probability of teleworking. We find that low-income workers are less likely to telework, and that females are more likely to work from home. Latent variables also played a relevant role at the beginning of the pandemic: a greater concern about health issues increased the probability of teleworking. In comparison, a greater concern about the economic effects of the pandemic had the opposite impact. However, these effects shifted 10 weeks into the pandemic, when a total lockdown was imposed in the largest city. The implications of our findings for both policy and research after the pandemic are discussed.
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    Extracorporeal membrane oxygenation for tuberculosis pneumonia with empyema
    (2021) Besa, Santiago; Morales, Alvaro J.; Salas, Patricio; Bravo M, Sebastian; Garrido-Olivares, Luis
    Acute respiratory distress syndrome (ARDS) caused by Mycobacterium Tuberculosis (TB) is a rare entity. Extracorporeal membrane oxygenation (ECMO) therapy had been used as an effective therapy for this cases, but the evidence is scarce. We present a case that took place in the middle of SARS-CoV2 pandemic. A 33-year-old female presented with ARDS due to pulmonary TB infection (pneumonia with empyema and pneumothorax), which required invasive mechanical ventilation with poor response. Long term veno-arterio-venous (VAV) ECMO, overlapped with veno-venous ECMO, was used as a salvage therapy with a good response for a total of 26 days. This is an example of the effectiveness of this therapy in this scenario, never described before. The fact that this therapy was used in the middle of SARS-CoV2 pandemic, with limited resources available, was remarkable, but it was encouraged by previous successful experiences.
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    Oncological resection, myasthenia gravis and staging as prognostic factors in thymic tumours: a Chilean case series
    (2021) Salas, Patricio; Solovera, Maria Eliana; Bannura, Felipe; Muñoz-Medel, Matias; Cordova-Delgado, Miguel; Sanchez, Cesar; Ibañez, Carolina; Garrido, Marcelo; Koch, Erica; Acevedo, Francisco; Mondaca, Sebastian; Nervi, Bruno; Madrid, Jorge; Peña, Jose; Pinto, Mauricio P.; Valbuena, José; Galindo, Hector
    Background: Thymic epithelial tumours are rare and highly heterogeneous. Reports from the United States suggest an overall incidence of 0.15 per 100,000/year. In contrast, the incidence of these tumours in Latin America is largely unknown and reports are scarce, somewhat limited to case reports. Methods: Herein, we report a series of 38 thymic tumours from a single institution, retrospectively incorporated into this study. Patient characteristics and outcomes including age, sex, stage, paraneoplastic syndromes, treatment regimens and the date of decease were obtained from medical records. Results: Most cases in our series were females and young age (<50 years old) and early stage by Masaoka-Koga or the Moran staging systems. Also, a 34% of patients had myasthenia gravis (MG). Next, we analysed overall survival rates in our series and found that the quality of surgery (R0, R1 or R2), MG status and staging (Masaoka-Koga, Moran or TNM) were prognostic factors. Finally, we compared our data to larger thymic tumour series. Conclusions: Overall, our study confirms complete surgical resection as the standard, most effective treatment for thymic epithelial tumours. Also, the Masaoka-Koga staging system remains as a reliable prognostic factor but also the Moran staging system should be considered for thymomas.