Browsing by Author "Santibanez, Helga"

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    A national online survey applied to patients with celiac disease in Chile
    (SOC MEDICA SANTIAGO, 2011) Espino, Alberto; Castillo L, Cecilia; Guiraldes, Ernesto; Santibanez, Helga; Francisco Miquel, Juan
    Background: Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. Its prevalence in Europe and the USA is 0.5 to 1%. Aim: To analyze epidemiological aspect's and degree of compliance with gluten-free diet (GFD) among Chilean individuals with CD. Material and Methods: Subjects with confirmed or suspected CD were invited to answer an online survey published on the web at www.ftmdacionconvivir.cl. The answers were reinforced with a telephone interview. Results: The survey was answered by 1212 subjects (79% females). Median age at diagnosis was 25.8 years (range 1 to 84 years), with a bimodal curve with two peaks at less than 3 years and at 20 to 40 years of age. The diagnosis was made only by serologic markers in 9%, only by intestinal biopsy in 17.5%, and by a combination of both methods in 70%. Conditions associated with CD were reported by 30% of subjects and 20% had relatives with CD. The GFD was strictly adhered to by 70%, occasionally by 27% and never by 3%. Seventy five percent of subjects with a strict adherence to GFD had a favorable clinical response compared with 42% of those with incomplete or lack of adherence (odds ratio 4.0, 95% confidence intervals 2.8-5.7 p < 0.01). Conclusions: In 30% of respondents, the diagnosis of CD was not confirmed according to international guidelines that require serology and duodenal biopsy. One third of subjects recognized a poor compliance with GFD. Those with a strict adherence to it had a more favorable clinical course. However, 25% did not experience a clinical improvement despite a strict GFD, a finding which requires further study (Rev Med Chile 2011; 139: 841-847).
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    Factors that limit adherence to diet and quality of life in Chilean celiac patients during COVID-19.
    (2021) Parada, Alejandra; Espino E, Alberto; Reyes, Alvaro; Santibanez, Helga
    Background. Coronavirus disease (COVID-19) is highly contagious and dynamic confinement measures have shown to significantly reduce the number of infections, however, they can alter the availability of food, affecting adherence to a gluten-free diet (GFD) and quality of life (QoL) in celiac disease (CD). The objective of this study was to evaluate the limiting factors, adherence to a gluten-free diet and quality of life in people with celiac disease in a COVID-19 pandemic period. Methods. On-line surveys were applied regarding adherence to the GFD, CV, and factors that have generated difficulty in carrying out a GFD in this setting. Results. 216 surveys of celiac patients over 15 years of age were analyzed, of which 91% were women with an average age of 36 + 10.7 years and with 5.8 + 6.0 years of the disease. 56.48% had excellent adherence to the GFD and 43.52% had a good QoL. The high cost of gluten-free foods was the question with the highest response percentage, associated with regular and poor adherence to the GFD (p-value = 0.001) and with poor QoL (p-value = 0.023). Conclusion. In a COVID-19 pandemic period, the cost of food is associated with regular and poor adherence to the GFD and with poor QoL. Arch Latinoam Nutr 2021; 71(1): 54-60.