Browsing by Author "Schwaar, Timm"

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    ADAMTS4-specific MR probe to assess aortic aneurysms in vivo using synthetic peptide libraries
    (2022) Kaufmann, Jan O.; Brangsch, Julia; Kader, Avan; Saatz, Jessica; Mangarova, Dilyana B.; Zacharias, Martin; Kempf, Wolfgang E.; Schwaar, Timm; Ponader, Marco; Adams, Lisa C.; Moeckel, Jana; Botnar, Rene M.; Taupitz, Matthias; Maegdefessel, Lars; Traub, Heike; Hamm, Bernd; Weller, Michael G.; Makowski, Marcus R.
    New biomarkers are required to improve the assessment of aortic wall integrity and risk of rupture. Here the authors report the development of an imaging probe for ADAMTS4, which they test in an abdominal aortic aneurysm mouse model and show in vivo prediction of aneurysm and rupture.