Browsing by Author "Stern, Dalia"

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    Cohort profile: the Cohorts Consortium of Latin America and the Caribbean (CC-LAC)
    (2020) Carrillo Larco, Rodrigo M.; Di Cesare, Mariachiara ; Hambleton, Ian R.; Hennis, Anselm; Irazola, Vilma; Stern, Dalia; Ferreccio Readi, Fresia Catterina; Lotufo, Paulo; Perel, Pablo; Gregg, Edward W.; Ezzati, Majid; Goodarz, Danaei; Miranda, J. Jaime; Aguilar-Salinas, Carlos A.; Álvarez Váz, Ramón; Amadio, Marselle B.; Baccino, Cecilia; Arenas, Sandra; Bambs Sandoval, Claudia Elena; Cortés Arancibia, Sandra Isabel; Cohorts Consortium of Latin America and the Caribbean (CC-LAC)
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    Derivation, internal validation, and recalibration of a cardiovascular risk score for Latin America and the Caribbean (Globorisk-LAC): A pooled analysis of cohort studies
    (2022) Carrillo-Larco, Rodrigo M.; Stern, Dalia; Hambleton, Ian R.; Lotufo, Paulo; Di Cesare, Mariachiara; Hennis, Anselm; Ferreccio, Catterina; Irazola, Vilma; Perel, Pablo; Gregg, Edward W.; Miranda, J. Jaime; Ezzati, Majid; Danaei, Goodarz
    Background Risk stratification is a cornerstone of cardiovascular disease (CVD) prevention and a main strategy proposed to achieve global goals of reducing premature CVD deaths. There are no cardiovascular risk scores based on data from Latin America and the Caribbean (LAC) and it is unknown how well risk scores based on European and North American cohorts represent true risk among LAC populations.
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    Impact of common cardio metabolic risk factors on fatal and non fatal cardiovascular disease in Latin America and the Caribbean: an individual level pooled analysis of 31 cohort studies
    (Elsevier Ltd, 2021) Carrillo-Larco, Rodrigo M.; Stern, Dalia; Hambleton, Ian; Hennis, Anselm; Cesare, Mariachiara Di; Lotufo, Paulo; Ferreccio Readi, Fresia Catterina; Irazola, Vilma; Perel, Pablo; Gregg, Edward W.; Miranda, J. Jaime; Ezzati, Majid; Goodarz, Danaei; Aguilar-Salinas, Carlos A.; Alvarez-Váz, Ramón; Marselle B., Amadio; Baccino, Cecilia; Bambs Sandoval, Claudia Elena; Bastos, Joao Luiz; Cortés Arancibia, Sandra Isabel; Cohorts Consortium of Latin America and the Caribbean (CC-LAC)
    Background: estimates of the burden of cardio-metabolic risk factors in Latin America and the Caribbean (LAC) rely on relative risks (RRs) from non-LAC countries. Whether these RRs apply to LAC remains unknown. Methods: We pooled LAC cohorts. We estimated RRs per unit of exposure to body mass index (BMI), systolic blood pressure (SBP), fasting plasma glucose (FPG), total cholesterol (TC) and non-HDL cholesterol on fatal (31 cohorts, n=168,287) and non-fatal (13 cohorts, n=27,554) cardiovascular diseases, adjusting for regression dilution bias. We used these RRs and national data on mean risk factor levels to estimate the number of cardiovascular deaths attributable to non-optimal levels of each risk factor. Results: Our RRs for SBP, FPG and TC were like those observed in cohorts conducted in high-income countries; however, for BMI, our RRs were consistently smaller in people below 75 years of age. Across risk factors, we observed smaller RRs among older ages. Non-optimal SBP was responsible for the largest number of attributable cardiovascular deaths ranging from 38 per 100,000 women and 54 men in Peru, to 261 (Dominica, women) and 282 (Guyana, men). For non-HDL cholesterol, the lowest attributable rate was for women in Peru (21) and men in Guatemala (25), and the largest in men (158) and women (142) from Guyana. Interpretation: RRs for BMI from studies conducted in high-income countries may overestimate disease burden metrics in LAC; conversely, RRs for SBP, FPG and TC from LAC cohorts are similar to those estimated from cohorts in high-income countries. Funding: Wellcome Trust (214185/Z/18/Z)
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    Life expectancy and mortality in 363 cities of Latin America
    (2021) Bilal, Usama; Hessel, Philipp; Perez-Ferrer, Carolina; Michael, Yvonne L.; Alfaro, Tania; Tenorio-Mucha, Janeth; Friche, Amelia A. L.; Pina, Maria Fatima; Vives, Alejandra; Quick, Harrison; Alazraqui, Marcio; Rodriguez, Daniel A.; Miranda, J. Jaime; Diez-Roux, Ana V.; Alazraqui, Marcio; Alazraqui, Marcio; Spinelli, Hugo; Guevel, Carlos; Di Cecco, Vanessa; Tisnes, Adela; Leveau, Carlos; Santoro, Adrian; Herkovits, Damian; Trotta, Andres; Aguirre, Patricia; Lopez, Santiago Rodriguez; Tumas, Natalia; Gouveia, Nelson; Mascolli, Maria Antonietta; Slovic, Anne Dorothee; Martins, Lucas Soriano; Kanai, Claudio Makoto; Barreto, Mauricio; Santos, Gervasio; de Freitas, Anderson Dias; De Castro, Caio Porto; Filho, Jose Firmino de Sousa; Bell, Maria Izabel dos Santos; Andrade, Roberto Fernandes Silva; Cardoso, Leticia; Menezes, Mariana Carvalho de; Pina, Maria de Fatima de; Skaba, Daniel Albert; Guimaraes, Joanna Miguez Nery; Matos, Vanderlei Pascoal de; Caiaffa, Waleska Teixeira; Friche, Amelia Augusta de Lima; Andrade, Amanda Cristina de Souza; Vaz, Camila Teixeira; Coelho, Debora Moraes; Sales, Denise Marques; Aguilar, Guilherme Aparecido Santos; Nascimento, Julia de Carvalho; Morais, Lidia Maria de Oliveira; Santos, Mariana de Melo; Silva, Uriel Moreira; Frenz, Patricia; Alfaro, Tania; Cordova, Cynthia; Ruiz, Pablo; Fuentes, Mauricio; Castillo, Marianela; Pedrero, Sebastian; Rodriguez, Lorena; Doberti, Tamara; Vergara, Alejandra Vives; Salazar, Alejandro; Cortinez-O'Ryan, Andrea; Schmitt, Cristian; Gonzalez, Francisca; Baeza, Fernando; Angelini, Flavia; Orlando, Laura; Sarmiento, Olga Lucia; Higuera, Diana; Gonzalez, Catalina; Montes, Felipe; Useche, Andres F.; Guaje, Oscar; Jaramillo, Ana Maria; Guzman, Luis Angel; Cuesta, Diego Lucumi; Guerra, John Alexis; Bonilla, Jorge Alexander; Guzman, Luis Angel; Linares, Mario; Hessel, Philipp; Morales, Ricardo; Triana, Camilo; Wilches, Maria Alejandra; Palacio, Alejandro; Pena, Fabian Camilo; Sabogal, Joaquin Hernando Jaramillo; Lopez, Julieth; Fajardo, Karen; Botero, Marcelo; Cely, Natalia; Martinez, Paola; Moncada, Carlos; Meisel, Jose David; Martinez, Eliana; Kroker-Lobos, Maria Fernanda; Ramirez-Zea, Manuel; Mazariegos, Monica; Morales, Anali; Barrientos-Gutierrez, Tonatiuh; Perez-Ferrer, Carolina; Prado-Galbarro, Javier; Lopez-Olmedo, Nancy Paulina; de Castro, Filipa; Rojas-Martinez, Rosalba; Jauregui, Alejandra; Stern, Dalia; Riojas, Horacio; Texcalac, Jose Luis; Perez, Desiree Vidana; Miranda, J. Jaime; Vasquez, Akram Hernandez; Diez-Canseco, Francisco; Garcia, Lorena Saavedra; Hammond, Ross; Rodriguez, Daniel; Dronova, Iryna; Wang, Xize; Moran, Mika; Zhao, Yuanyuan; Ju, Yang; Delclos-Alio, Xavier; Hovmand, Peter; Ballard, Ellis; Kuhlberg, Jill; Diez-Roux, Ana V.; Auchincloss, Amy; Barber, Sharrelle; Bilal, Usama; Garcia-Espana, Felipe; Langellier, Brent; Lovasi, Gina; McClure, Leslie; Michael, Yvonne; Moore, Kari; Ortigoza, Ana; Quick, Harrison; Quistberg, D. Alex; Sanchez, Brisa N.; Stankov, Ivana; Tapia-Granados, Jose; Yamada, Goro; Rodriguez-Hernandez, Jordan; Melly, Steve; Avila-Palencia, Ione; Kephart, Josiah; Mullachery, Pricila; Trejo, Bricia; Braverman, Ariela; Fry, Dustin; Henson, Rosie Mae; Martinez-Folgar, Kevin; Slesinski, S. Claire; Indvik, Katherine; Bolinaga, Andrea
    The concept of a so-called urban advantage in health ignores the possibility of heterogeneity in health outcomes across cities. Using a harmonized dataset from the SALURBAL project, we describe variability and predictors of life expectancy and proportionate mortality in 363 cities across nine Latin American countries. Life expectancy differed substantially across cities within the same country. Cause-specific mortality also varied across cities, with some causes of death (unintentional and violent injuries and deaths) showing large variation within countries, whereas other causes of death (communicable, maternal, neonatal and nutritional, cancer, cardiovascular disease and other noncommunicable diseases) varied substantially between countries. In multivariable mixed models, higher levels of education, water access and sanitation and less overcrowding were associated with longer life expectancy, a relatively lower proportion of communicable, maternal, neonatal and nutritional deaths and a higher proportion of deaths from cancer, cardiovascular disease and other noncommunicable diseases. These results highlight considerable heterogeneity in life expectancy and causes of death across cities of Latin America, revealing modifiable factors that could be amenable to urban policies aimed toward improving urban health in Latin America and more generally in other urban environments.