Browsing by Author "Troconiz, Inaki F."

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    Obesity Does Not Influence the Onset and Offset of Sevoflurane Effect as Measured by the Hysteresis Between Sevoflurane Concentration and Bispectral Index
    (LIPPINCOTT WILLIAMS & WILKINS, 2011) Cortinez, Luis I.; Gambus, Pedro; Troconiz, Inaki F.; Echevarria, Ghislaine; Munoz, Hernan R.
    BACKGROUND: The onset and offset of action of anesthetic gases might be delayed by respiratory changes and gas exchange alterations present in obese patients. In this study, we assessed the influence of obesity on the hysteresis between sevoflurane and its effect as measured by the bispectral index (BIS). Because the use of positive end-expiratory pressure (PEEP) in obese patients has improved gas exchange, we also assessed the influence of PEEP on hysteresis.
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    The Influence of Age on the Dynamic Relationship Between End-Tidal Sevoflurane Concentrations and Bispectral Index
    (LIPPINCOTT WILLIAMS & WILKINS, 2008) Cortinez, Luis I.; Troconiz, Inaki F.; Fuentes, Ricardo; Gambus, Pedro; Hsu, Yung Wei; Altermatt, Fernando; Munoz, Hernan R.
    BACKGROUND: Age is an important determinant of the pharmacokinetic profile of inhaled anesthetics. The influence of age on the dynamic profile of sevoflurane's effect has not been well described. We performed this study to characterize the influence of age and other covariates on the dynamic relationship between sevoflurane end-tidal concentration (C-ET) and its effect measured by bispectral index (BIS).