PLASMA-ALDOSTERONE RESPONSE TO ANGIOTENSIN-11 AND KCL INFUSIONS IN HYPOPITUITARY PATIENTS

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dc.contributor.authorLOPEZ, JM
dc.contributor.authorRODRIGUEZ, JA
dc.contributor.authorMARUSIC, ET
dc.date.accessioned2025-01-23T19:44:31Z
dc.date.available2025-01-23T19:44:31Z
dc.date.issued1980
dc.description.abstractThe acute adrenal response to KCl and angiotensin II (A II) infusions was studied in hypopituitary patients and compared with normal subjects. The peripheral plasma levels of aldosterone (PAC), cortisol, K and plasma renin activity, were measured at 0900 h and after 60 and 120 min of infusion. All subjects were recumbent and under balance conditions, receiving a daily dietary intake of 180 mmol of Na and 80 mmol of K. Basal PAC in hypopituitary patients was not significantly different from that observed in the control group. Both normal and hypopituitary patients respond to A II infusion with significant increments. Under KCl stimulus the PAC response in hypopituitary patients was only observed when cortisol (20 mg) was given 2 h prior to the infusion. When cortisol replacement was omitted the response to KCl was not detected. These results suggest a permissive role of cortisol on glomerulosa response to K.
dc.fuente.origenWOS
dc.identifier.eissn1365-2265
dc.identifier.issn0300-0664
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/100062
dc.identifier.wosidWOS:A1980KL23400003
dc.issue.numero4
dc.language.isoen
dc.pagina.final337
dc.pagina.inicio331
dc.revistaClinical endocrinology
dc.rightsacceso restringido
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titlePLASMA-ALDOSTERONE RESPONSE TO ANGIOTENSIN-11 AND KCL INFUSIONS IN HYPOPITUITARY PATIENTS
dc.typeartículo
dc.volumen13
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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