Teneurin protein family: an emerging role in human tumorigenesis and drug resistance

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dc.catalogadorpau
dc.contributor.authorZiegler, Annemarie
dc.contributor.authorCorvalán Rodríguez, Alejandro
dc.contributor.authorRoa, Iván
dc.contributor.authorBrañes Yunusic, Jorge Antonio
dc.contributor.authorWollscheid, Bernd
dc.date.accessioned2024-06-09T20:06:17Z
dc.date.available2024-06-09T20:06:17Z
dc.date.issued2012
dc.description.abstractUsing a chemoproteomic strategy, we recently demonstrated the expression of teneurin-2, a transmembrane glycoprotein, in the majority of malignant mesothelioma cell lines. This finding was unexpected since no formally organized evidence existed to implicate teneurins in human malignancy. For this reason, here we provide a comprehensive review on the expression of teneurins in human tumors and cell lines. Current evidence supports the aberrant expression of teneurins in various tumor types, their involvement in cancer-related regulatory networks, and their potential participation in drug resistance. Structural attributes of teneurins could enable the detection of shedded forms in body fluids for clinical applications. (C) 2012 Elsevier Ireland Ltd. All rights reserved.
dc.description.funderFondecyt no. 1100605 (A.Z.)
dc.description.funderNational Center of Competence in Research (NCCR)
dc.description.funderNeural Plasticity and Repair (B.W.)
dc.fechaingreso.objetodigital2024-06-10
dc.fuente.origenHistorial Académico
dc.identifier.doi10.1016/J.CANLET.2012.07.021
dc.identifier.issn0304-3835
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/86650
dc.identifier.urihttps://doi.org/10.1016/J.CANLET.2012.07.021
dc.identifier.wosidWOS:000309486600001
dc.information.autorucEscuela de Medicina; Brañes Yunusic, Jorge Antonio; S/I; 76860
dc.information.autorucEscuela de Medicina;Corvalán Rodríguez, Alejandro;0000-0001-5492-3853; 63885
dc.issue.numero1
dc.language.isoen
dc.nota.accesocontenido parcial
dc.pagina.final7
dc.pagina.inicio1
dc.revistaCancer Letters
dc.rightsacceso restringido
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleTeneurin protein family: an emerging role in human tumorigenesis and drug resistance
dc.typeartículo
dc.volumen326
sipa.codpersvinculados76860
sipa.codpersvinculados63885
sipa.trazabilidadHistorial Académico;09-07-2021
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