High prevalence of vitamin D deficiency in Chilean healthy postmenopausal women with normal sun exposure: additional evidence for a worldwide concern

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dc.contributor.authorGonzalez, Gilberto
dc.contributor.authorAlvarado, Jose N.
dc.contributor.authorRojas, Auristela
dc.contributor.authorNavarrete, Carlos
dc.contributor.authorVelasquez, Carmen G.
dc.contributor.authorArteaga, Eugenio
dc.date.accessioned2024-01-10T12:05:50Z
dc.date.available2024-01-10T12:05:50Z
dc.date.issued2007
dc.description.abstractObjective: To assess the prevalence of vitamin D deficiency in healthy postmenopausal women with normal sun exposure but without vitamin D fortification in their diets.
dc.description.abstractDesign: We studied 90 healthy, ambulatory women who were residents of Santiago, Chile (latitude 33 degrees S); 30 were premenopausal (32.6 +/- 7.4 y), and 60 were postmenopausal (63.7 +/- 9.7 y). Half of the women were studied during the winter and the other half during the following summer. Each provided a fasting blood sample to measure biochemical parameters, parathyroid hormone, and 25-hydroxyvitamin D and completed a questionnaire to estimate sunlight exposure. A first morning urine sample was collected in postmenopausal women to measure deoxypyridinoline. Various cutoff points of 25-hydroxyvitamin D were used to assess the prevalence of vitamin D deficiency (< 9, < 15, and < 20 ng/mL).
dc.description.abstractResults: All of the women had normal renal and liver parameters. Sunlight exposure was adequate in almost all of the volunteers (93% in both groups, P > 0.05). In postmenopausal women, serum 25-hydroxyvitamin D was less than 9 ng/mL in 12%, less than 15 ng/mL in 40%, and less than 20 ng/mL in 60%, compared with 0%, 13%, and 27%, respectively, in premenopausal women. Deoxypyridinoline was 75% higher during winter than summer (9.8 +/- 2.5 vs 5.6 +/- 1.4 nmol/mmol creatinine, P < 0.0001).
dc.description.abstractConclusions: Vitamin D deficiency is very common in Chilean healthy postmenopausal women with normal sun exposure but without vitamin D fortification in their diets. This finding is associated with higher bone resorption during winter time and emphasizes the need to increase vitamin D intake in healthy postmenopausal women.
dc.fechaingreso.objetodigital2024-05-09
dc.format.extent7 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1097/GME.0b013e31802c54c0
dc.identifier.issn1072-3714
dc.identifier.pubmedidMEDLINE:17290161
dc.identifier.urihttps://doi.org/10.1097/GME.0b013e31802c54c0
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/76075
dc.identifier.wosidWOS:000246374500019
dc.information.autorucMedicina;Arteaga E;S/I;98586
dc.information.autorucMedicina;González G;S/I;100244
dc.issue.numero3
dc.language.isoen
dc.nota.accesoSin adjunto
dc.pagina.final461
dc.pagina.inicio455
dc.publisherLIPPINCOTT WILLIAMS & WILKINS
dc.revistaMENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY
dc.rightsregistro bibliográfico
dc.subjectvitamin D
dc.subjectvitamin D deficiency
dc.subjectmenopause
dc.subjecthyperparathyroidism
dc.subjectosteoporosis
dc.subjectaging
dc.subjectHYPOVITAMINOSIS-D
dc.subjectD INSUFFICIENCY
dc.subjectSECONDARY HYPERPARATHYROIDISM
dc.subjectSOLAR ULTRAVIOLET
dc.subjectD SUPPLEMENTATION
dc.subjectYOUNG-ADULTS
dc.subjectMETAANALYSIS
dc.subjectFRACTURE
dc.subject25-HYDROXYVITAMIN-D
dc.subjectDETERMINANTS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleHigh prevalence of vitamin D deficiency in Chilean healthy postmenopausal women with normal sun exposure: additional evidence for a worldwide concern
dc.typeartículo
dc.volumen14
sipa.codpersvinculados98586
sipa.codpersvinculados100244
sipa.indexWOS
sipa.trazabilidadCarga SIPA;09-01-2024
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