Helicobacter pylori infection and UBT-13C values are associated with changes in body mass index in children and adults

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dc.catalogadoraba
dc.contributor.authorBruera, María J.
dc.contributor.authorAmezquita García, María Virginia
dc.contributor.authorRiquelme Pérez, Arnoldo
dc.contributor.authorSerrano Honeyman, Carolina
dc.contributor.authorHarris D., Paul R.
dc.date.accessioned2024-01-17T19:36:07Z
dc.date.available2024-01-17T19:36:07Z
dc.date.issued2022
dc.description.abstractBackground: The urea breath test (UBT-13C) is a non-invasive technique that allows the diagnosis and confirmation of eradication of Helicobacter pylori infection. Aim: To evaluate H. pylori positivity and values of UBT-13C among infected Chilean children and adults, and to analyze its variation in relation to sex, nutritional status, and age of the patients. Material and Methods: Retrospective study of 1141 patients aged 6 to 94 years, with an indication for a UBT-13C either for diagnosis or for confirmation of eradication of H. pylori infection. 13C enrichment was measured using an infrared spectrometer calculating the delta 13C values before and after the ingestion of 13C marked urea. The clinical data of the patients were obtained at the time of the examination. Results: We included 241 children and 900 adults. Infected children obtained lower UBT-13C delta values than infected adults (16.1 ± 8.7 and 37 ± 52.9, respectively). The rates of infection were higher in males who were recruited for diagnosis. Significant differences were obtained between positivity for H. pylori in overweight and obese children but not adults. UBT-13C titers were significantly associated with the body mass index (BMI) only in adults. Conclusions: H. pylori infection rates are similar between sexes and are higher in children probably because of selection bias. In children, H. pylori positivity is associated with higher BMI and excess malnutrition although with similar UBT-13C values. In adults, H. pylori infection is not related with BMI, but a higher BMI impacts UBT-13C titers.
dc.fechaingreso.objetodigital2024-01-19
dc.format.extent10 páginas
dc.fuente.origenORCID-ene24
dc.identifier.doi10.4067/S0034-98872022001101467
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.scopusidSCOPUS_ID:85161652941
dc.identifier.urihttps://doi.org/10.4067/S0034-98872022001101467
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/80583
dc.information.autorucEscuela de Medicina; Amezquita García, María Virginia; 0009-0009-4494-7590; 70478
dc.information.autorucEscuela de Medicina; Riquelme Pérez, Arnoldo; 0000-0002-8259-8960; 3538
dc.information.autorucEscuela de Medicina; Serrano Honeyman, Carolina; 0000-0001-5523-0637; 15296
dc.information.autorucEscuela de Medicina; Harris D., Paul R.; 0000-0001-6226-0957; 80706
dc.issue.numero11
dc.language.isoen
dc.nota.accesoContenido completo
dc.pagina.final1476
dc.pagina.inicio1467
dc.revistaRevista Médica de Chile
dc.rightsacceso abierto
dc.rights.licenseCC BY 4.0 DEEDAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.en
dc.subjectBody Mass Index
dc.subjectBreath Tests
dc.subjectHelicobacter pylori
dc.subjectUrea
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.ods02 Zero hunger
dc.subject.odspa03 Salud y bienestar
dc.subject.odspa02 Hambre cero
dc.titleHelicobacter pylori infection and UBT-13C values are associated with changes in body mass index in children and adults
dc.title.alternativeLa infección por Helicobacter pylori y los valores de UBT-13C se asocian con el índice de masa corporal en niños y adultos
dc.typeartículo
dc.volumen150
sipa.codpersvinculados70478
sipa.codpersvinculados3538
sipa.codpersvinculados15296
sipa.codpersvinculados80706
sipa.indexSCOPUS
sipa.trazabilidadORCID;2024-01-08
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