Antenatal Exposure to Magnesium Sulphate and Neonatal Outcomes in Very Low Birth Weight Infants: a multicenter study.

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dc.catalogadorjlo
dc.contributor.authorFerreira, María Vaz
dc.contributor.authorCaro, José
dc.contributor.authorVillarroel, Luis
dc.contributor.authorMuñoz, Sergio
dc.contributor.authorÁlvarez, Patricia
dc.contributor.authorFlores, Gerardo
dc.contributor.authorHerrera, Tamara
dc.contributor.authorToso Milos, Alberto Antonio
dc.contributor.authorToso Milos Paulina Alejandra
dc.contributor.authorTapia, José
dc.date.accessioned2023-09-26T19:05:58Z
dc.date.available2023-09-26T19:05:58Z
dc.date.issued2023
dc.description.abstractObjective: To explore the association between antenatal magnesium sulphate ( MgSO4 ), mortality and incidence of intraventricular hemorrhage (IVH) in very low birth weight (VLBW) infants. Study design: Retrospective, cohort study of infants < 32 weeks’ GA born at centers of NEOCOSUR Network between January 2015 and December 2020. Subjects were categorized as exposed vs non-exposed to antenatal MgSO4. Primary outcomes were death, incidence of severe IVH (Grade III-IV) and severe IVH/death. Secondary outcomes included relevant morbidities. Results: 7418 VLBW infants were eligible. Antenatal MgSO4 was associated with a signicantly decreased death rate after admission (aOR 0.59 [95% CI, 0.46–0.74]) and severe IVH/ death (aOR 0.63 [95% CI, 0.490.83]). No signicant reduction in severe IVH was observed (aOR 0.89 [95% CI, 0.63–1.25]). No differences between groups were observed in rates of morbidities. Conclusion: Antenatal MgSO4 was associated with a decreased death rate after admission and in severe IVH/ death.
dc.fechaingreso.objetodigital2023-09-26
dc.format.extent11 páginas
dc.fuente.origenSIPA
dc.identifier.doi10.21203/rs.3.rs-3311524/v1
dc.identifier.issn2693-5015
dc.identifier.urihttps://doi.org/10.21203/rs.3.rs-3311524/v1
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/74702
dc.information.autorucEscuela de Medicina; Toso Milos, Alberto Antonio; 0000-0002-3809-2567; 238020
dc.information.autorucEscuela de Medicina; Toso Milos Paulina Alejandra; 0000-0001-8872-2347; 1001239
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final11
dc.pagina.inicio1
dc.revistaResearch Square
dc.rightsacceso restringido
dc.subjectAntenatal Magnesium Sulphate
dc.subjectVery Low Birth Weight Infants
dc.subjectIntraventricular Hemorrhage
dc.subjectMortality
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleAntenatal Exposure to Magnesium Sulphate and Neonatal Outcomes in Very Low Birth Weight Infants: a multicenter study.
dc.typepreprint
sipa.codpersvinculados238020
sipa.codpersvinculados1001239
sipa.trazabilidadORCID;2023-09-25
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