A national online survey applied to patients with celiac disease in Chile

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dc.contributor.authorEspino, Alberto
dc.contributor.authorCastillo L, Cecilia
dc.contributor.authorGuiraldes, Ernesto
dc.contributor.authorSantibanez, Helga
dc.contributor.authorFrancisco Miquel, Juan
dc.date.accessioned2024-01-10T12:04:12Z
dc.date.available2024-01-10T12:04:12Z
dc.date.issued2011
dc.description.abstractBackground: Celiac disease (CD) is an immune-mediated enteropathy triggered by the ingestion of gluten in genetically susceptible individuals. Its prevalence in Europe and the USA is 0.5 to 1%. Aim: To analyze epidemiological aspect's and degree of compliance with gluten-free diet (GFD) among Chilean individuals with CD. Material and Methods: Subjects with confirmed or suspected CD were invited to answer an online survey published on the web at www.ftmdacionconvivir.cl. The answers were reinforced with a telephone interview. Results: The survey was answered by 1212 subjects (79% females). Median age at diagnosis was 25.8 years (range 1 to 84 years), with a bimodal curve with two peaks at less than 3 years and at 20 to 40 years of age. The diagnosis was made only by serologic markers in 9%, only by intestinal biopsy in 17.5%, and by a combination of both methods in 70%. Conditions associated with CD were reported by 30% of subjects and 20% had relatives with CD. The GFD was strictly adhered to by 70%, occasionally by 27% and never by 3%. Seventy five percent of subjects with a strict adherence to GFD had a favorable clinical response compared with 42% of those with incomplete or lack of adherence (odds ratio 4.0, 95% confidence intervals 2.8-5.7 p < 0.01). Conclusions: In 30% of respondents, the diagnosis of CD was not confirmed according to international guidelines that require serology and duodenal biopsy. One third of subjects recognized a poor compliance with GFD. Those with a strict adherence to it had a more favorable clinical course. However, 25% did not experience a clinical improvement despite a strict GFD, a finding which requires further study (Rev Med Chile 2011; 139: 841-847).
dc.format.extent7 páginas
dc.fuente.origenWOS
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:22051820
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75722
dc.identifier.wosidWOS:000293874000003
dc.information.autorucMedicina;Espino A ;S/I;146018
dc.information.autorucMedicina;Miquel J;S/I;72216
dc.issue.numero7
dc.language.isoes
dc.nota.accesoSin adjunto
dc.pagina.final847
dc.pagina.inicio841
dc.publisherSOC MEDICA SANTIAGO
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsregistro bibliográfico
dc.subjectBiopsy
dc.subjectCeliac disease
dc.subjectDiet, gluten free
dc.subjectGLUTEN-FREE DIET
dc.subjectPREVALENCE
dc.subjectMULTICENTER
dc.subjectPOPULATION
dc.subjectDIAGNOSIS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleA national online survey applied to patients with celiac disease in Chile
dc.typeartículo
dc.volumen139
sipa.codpersvinculados146018
sipa.codpersvinculados72216
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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