Characterization of paracetamol overdose. Report of a poison information center in Chile

Simple item page
dc.contributor.authorBravo, Victoria
dc.contributor.authorRoman, Matias
dc.contributor.authorBettini, Marli
dc.contributor.authorCerda, Patricia
dc.contributor.authorJose Mieres, Juan
dc.contributor.authorParis, Enrique
dc.contributor.authorCarlos Rios, Juan
dc.date.accessioned2024-01-10T12:04:35Z
dc.date.available2024-01-10T12:04:35Z
dc.date.issued2012
dc.description.abstractBackground: Paracetamol (acetaminophen) is an analgesic and antipyretic drug widely used across the world. Its ingestion is one of the most common causes of drug overdose. In the United States is the first cause of acute hepatitis in adults. Aim: To describe the epidemiological profile of paracetamol overdose in Chile. Material and Methods: Cross sectional retrospective study that included all the phone call inquiries received at the Poison Control Center of the Pontificia Universidad Catolica de Chile (CITUC) during 2009. Results: Nine hundred fifty nine inquiries involving acute paracetamol exposures were received. Women represented a 63.1% of the cases. Half of the cases were suicide attempts, of which 74.8% were women. Accidental exposures occurred mainly in children. In 29.3% of the patients, the exposure was considered to involve a hepatotoxic dose. Women had 2.7 times the risk of men to ingest a toxic dose of paracetamol with suicidal purpose (Odds ratio (OR) = 2.7; 95% confidence interval (CI): 2.1-3.6; p < 0.001). Adolescents had 3.4 times the risk of the general consultants (OR: 3.4; 95% CI: 2.4-4.7; p < 0.001). Conclusions: Paracetamol overdose is common in Chile. Authorities should carry out preventive measures. Antidotes and the capacity to measure plasma levels of paracetamol should be available in healthcare centers. (Rev Med Chile 2012; 140: 313-318).
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:22689110
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/75837
dc.identifier.wosidWOS:000302927100005
dc.information.autorucMedicina;Bettini M ;S/I;9918
dc.information.autorucMedicina;Bravo V;S/I;16719
dc.information.autorucMedicina;Cerda P;S/I;9919
dc.information.autorucMedicina;Mieres J;S/I;16966
dc.information.autorucMedicina;Paris E ;S/I;99451
dc.information.autorucMedicina;Rios J;S/I;104168
dc.information.autorucMedicina;Roman M ;S/I;156243
dc.issue.numero3
dc.language.isoes
dc.nota.accesoSin adjunto
dc.pagina.final318
dc.pagina.inicio313
dc.publisherSOC MEDICA SANTIAGO
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsregistro bibliográfico
dc.subjectAcetaminophen
dc.subjectEpidemiology
dc.subjectPoisoning
dc.subjectPoison control centers
dc.subjectSuicide
dc.subjectACETAMINOPHEN
dc.subjectSUICIDE
dc.subjectAVAILABILITY
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleCharacterization of paracetamol overdose. Report of a poison information center in Chile
dc.typeartículo
dc.volumen140
sipa.codpersvinculados9918
sipa.codpersvinculados16719
sipa.codpersvinculados9919
sipa.codpersvinculados16966
sipa.codpersvinculados99451
sipa.codpersvinculados104168
sipa.codpersvinculados156243
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
2024-06-13. Characterization of paracetamol overdose. Report of a poison information center in Chile.pdf
Size:
3.05 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas