Comparison of LED- and LASER-based fNIRS technologies to record the human peri-spinal cord neurovascular response

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dc.contributor.authorCaulier-Cisterna, Raill
dc.contributor.authorAppelgren-Gonzales, Juan -Pablo
dc.contributor.authorOyarzun, Juan -Esteban
dc.contributor.authorValenzuela, Felipe
dc.contributor.authorSitaram, Ranganatha
dc.contributor.authorEblen-Zajjur, Antonio
dc.contributor.authorUribe, Sergio
dc.date.accessioned2025-01-20T16:17:03Z
dc.date.available2025-01-20T16:17:03Z
dc.date.issued2024
dc.description.abstractRecently, functional Near-Infrared Spectroscopy (fNIRS) was applied to obtain, non-invasively, the human peri-spinal Neuro-Vascular Response (NVR) under a non-noxious electrical stimulation of a peripheral nerve. This method allowed the measurements of changes in the concentration of oxyhemoglobin (O2Hb) and deoxyhemoglobin (HHb) from the peri-spinal vascular network. However, there is a lack of clarity about the potential differences in perispinal NVR recorded by the different fNIRS technologies currently available. In this work, the two main noninvasive fNIRS technologies were compared, i.e., LED and LASER-based. The recording of the human peri-spinal NVR induced by non-noxious electrical stimulation of a peripheral nerve was recorded simultaneously at C7 and T10 vertebral levels. The amplitude, rise time, and full width at half maximum duration of the perispinal NVRs were characterized in healthy volunteers and compared between both systems. The main difference was that the LED-based system shows about one order of magnitude higher values of amplitude than the LASER-based system. No statistical differences were found for rise time and for duration parameters (at thoracic level). The comparison of point-to-point wave patterns did not show significant differences between both systems. In conclusion, the peri-spinal NRV response obtained by different fNIRS technologies was reproducible, and only the amplitude showed differences, probably due to the power of the system which should be considered when assessing the human peri-spinal vascular network.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.medengphy.2024.104170
dc.identifier.eissn1873-4030
dc.identifier.issn1350-4533
dc.identifier.urihttps://doi.org/10.1016/j.medengphy.2024.104170
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/90578
dc.identifier.wosidWOS:001233366800001
dc.language.isoen
dc.revistaMedical engineering & physics
dc.rightsacceso restringido
dc.subjectNear-infrared spectroscopy
dc.subjectSpinal neurovascular response
dc.subjectNon-invasive method
dc.subjectSpinal neuronal activity
dc.subjectNeuro-vascular coupling
dc.subjectLED-fNIRS
dc.subjectLASER-fNIRS
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleComparison of LED- and LASER-based fNIRS technologies to record the human peri-spinal cord neurovascular response
dc.typeartículo
dc.volumen127
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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