Reconocimiento de influenza-A como etiología de síndrome febril e insuficiencia respiratoria en adultos hospitalizados durante brote en la comunidad

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dc.catalogadorpva
dc.contributor.authorRabagliati Borie, Ricardo Miguel
dc.contributor.authorBenítez Gómez, Rosana
dc.contributor.authorFernández Montenegro, María Alicia
dc.contributor.authorGaete Gutiérrez, Pablo Antonio
dc.contributor.authorGuzmán Durán, Ana María
dc.contributor.authorGarcía Cañete, Patricia
dc.contributor.authorFerrés, Marcela
dc.contributor.authorPérez Cortés, Carlos Miguel
dc.contributor.authorLabarca L., Jaime
dc.date.accessioned2025-03-19T20:09:33Z
dc.date.available2025-03-19T20:09:33Z
dc.date.issued2004
dc.description.abstractBackground: Influenza-A (IA) occurs every winter, is mostly observed among outpatients. Aim: To describe the clinical and epidemiological characteristics of cases that required hospital admission during an outbreak in Chile in 1999. Patients and methods: Adults subjects, with Influenza A confirmed by antigen detection test, hospitalized in the clinical hospital of the «Hospital Clínico de la Universidad Católica de Chile» between May and June, with fever or respiratory symptoms were studied. A special record was designed to register clinical, microbiological and therapeutic data. Results: Fifty five cases, 26 males, aged 15 to 91 years, were studied. Eighty four percent had chronic concomitant diseases and 9.1% were immunosuppressed. Clinical findings were fever in 87.3%, asthenia in 83.6%, cough in 93.6%, abnormal pulmonary signs in 69%, an elevated C-reactive protein (mean value of 11.6 ± 7.1 mg/dL) and acute respiratory insufficiency in 54.5%. Cases were isolated in cohort or individual rooms and 38.2% were admitted to intensive or intermediate care units. Amantadine was prescribed to 52 patients and was well tolerated. Thirty three percent of cases developed pneumonia. These subjects were older, had more dyspnea and respiratory insufficiency than patients without pneumonia. Conclusions: IA should be borne in mind when dealing with hospitalized adults, during epidemic outbreaks in the community. The clinical picture can resemble a serious bacterial infection. An early diagnosis allows the use of specific treatments, to decrease the risk of nosocomial spread and to avoid unnecessary use of antibiotics.
dc.fechaingreso.objetodigital2025-03-19
dc.format.extent8 páginas
dc.fuente.origenScopus
dc.fuente.origenORCID
dc.identifier.doi10.4067/S0034-98872004000300006
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:15376568
dc.identifier.scopusidSCOPUS_ID:12344290114
dc.identifier.urihttps://doi.org/10.4067/S0034-98872004000300006
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/102837
dc.identifier.wosidWOS:000228070100006
dc.information.autorucEscuela de Medicina; Rabagliati Borie, Ricardo Miguel; 0000-0002-0574-8312; 59169
dc.information.autorucEscuela de Medicina; Benítez Gómez, Rosana; S/I; 102074
dc.information.autorucEscuela de Medicina; Fernández Montenegro, María Alicia; S/I; 102169
dc.information.autorucEscuela de Medicina; Gaete Gutiérrez, Pablo Antonio; S/I; 5380
dc.information.autorucEscuela de Medicina; Guzmán Durán, Ana María; S/I; 77951
dc.information.autorucEscuela de Medicina; García Cañete, Patricia; 0000-0002-3817-4896; 73909
dc.information.autorucEscuela de Medicina; Ferrés, Marcela; 0000-0001-9415-4657; 66180
dc.information.autorucEscuela de Medicina; Pérez Cortés, Carlos Miguel; S/I; 66650
dc.information.autorucEscuela de Medicina; Labarca L., Jaime; S/I; 62874
dc.issue.numero3
dc.language.isoes
dc.nota.accesocontenido completo
dc.pagina.final324
dc.pagina.inicio317
dc.revistaRevista Médica de Chile
dc.rightsacceso abierto
dc.rights.licenseAtribución/Reconocimiento 4.0 Internacional
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/deed.es
dc.subjectInfluenza A virus, human
dc.subjectPneumonia, viral
dc.subjectRespiratory distress syndrome, adult
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleReconocimiento de influenza-A como etiología de síndrome febril e insuficiencia respiratoria en adultos hospitalizados durante brote en la comunidad
dc.title.alternativeInfluenza-A as etiology of fever and respiratory insufficiency in adults hospitalized during an outbreak in Chile
dc.typeartículo
dc.volumen132
sipa.codpersvinculados59169
sipa.codpersvinculados102074
sipa.codpersvinculados102169
sipa.codpersvinculados5380
sipa.codpersvinculados77951
sipa.codpersvinculados73909
sipa.codpersvinculados66180
sipa.codpersvinculados66650
sipa.codpersvinculados62874
sipa.trazabilidadORCID;2025-03-03
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