A cross sectional study found differential risks for COVID-19 seropositivity amongst health care professionals in Chile

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dc.contributor.authorZuniga, Marcela
dc.contributor.authorLagomarcino, Anne J.
dc.contributor.authorMunoz, Sergio
dc.contributor.authorPena Alonso, Alfredo
dc.contributor.authorAndrea Rodriguez, Maria
dc.contributor.authorO'Ryan, Miguel L.
dc.date.accessioned2025-01-20T21:08:36Z
dc.date.available2025-01-20T21:08:36Z
dc.date.issued2022
dc.description.abstractObjective: Health care workers (HCWs) are at increased risk for SARS-CoV-2 infection, however not all face the same risk. We aimed to determine IgG/IgM prevalence and risk factors associated with seropositivity in Chilean HCWs.
dc.description.abstractStudy Design and Setting: This was a nationwide, cross-sectional study including a questionnaire and COVID-19 lateral flow IgG/IgM antibody testing. All HCWs in the Chilean public health care system were invited to participate following the country's first wave.
dc.description.abstractResults: IgG/IgM positivity in 85,529 HCWs was 7.2%, ranging from 1.6% to 12.4% between regions. Additionally, 9.7% HCWs reported a positive PCR of which 47% were seropositive. Overall, 10,863 (12.7%) HCWs were PCR and/or IgG/IgM positive. Factors independently associated with increased odds ratios (ORs) for seropositivity were: working in a hospital, night shifts, contact with Covid-19, using public transport, male gender, age >45, BMI >= 30, and reporting >= 2 symptoms. Stress and/or mental health disorder and smoking were associated with decreased ORs. These factors remained significant when including PCR positive cases in the model.
dc.description.abstractConclusions: HCWs in the hospital were at highest risk for COVID-19, and several independent risk factors for seropositivity and/or PCR positivity were identified. (C) 2021 Elsevier Inc. All rights reserved.
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.jclinepi.2021.12.026
dc.identifier.eissn1878-5921
dc.identifier.issn0895-4356
dc.identifier.urihttps://doi.org/10.1016/j.jclinepi.2021.12.026
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/93482
dc.identifier.wosidWOS:000786657100005
dc.language.isoen
dc.pagina.final83
dc.pagina.inicio72
dc.revistaJournal of clinical epidemiology
dc.rightsacceso restringido
dc.subjectHealth care workers
dc.subjectCOVID-19
dc.subjectAntibody prevalence
dc.subjectVaccine priority
dc.subjectSARS-CoV-2
dc.subjectAntibody testing
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleA cross sectional study found differential risks for COVID-19 seropositivity amongst health care professionals in Chile
dc.typeartículo
dc.volumen144
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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