The face and its emotion: Right N170 deficits in structural processing and early emotional discrimination in schizophrenic patients and relatives

Simple item page
dc.contributor.authorIbanez, Agustin
dc.contributor.authorRiveros, Rodrigo
dc.contributor.authorHurtado, Esteban
dc.contributor.authorGleichgerrcht, Ezequiel
dc.contributor.authorUrquina, Hugo
dc.contributor.authorHerrera, Eduar
dc.contributor.authorAmoruso, Lucia
dc.contributor.authorMartin Reyes, Migdyrai
dc.contributor.authorManes, Facundo
dc.date.accessioned2024-01-10T13:43:48Z
dc.date.available2024-01-10T13:43:48Z
dc.date.issued2012
dc.description.abstractPrevious studies have reported facial emotion recognition impairments in schizophrenic patients, as well as abnormalities in the N170 component of the event-related potential. Current research on schizophrenia highlights the importance of complexly-inherited brain-based deficits. In order to examine the N170 markers of face structural and emotional processing, DSM-IV diagnosed schizophrenia probands (n = 13), unaffected first-degree relatives from multiplex families (n = 13), and control subjects (n = 13) matched by age, gender and educational level, performed a categorization task which involved words and faces with positive and negative valence. The N170 component, while present in relatives and control subjects, was reduced in patients, not only for faces, but also for face-word differences, suggesting a deficit in structural processing of stimuli. Control subjects showed N170 modulation according to the valence of facial stimuli. However, this discrimination effect was found to be reduced both in patients and relatives. This is the first report showing N170 valence deficits in relatives. Our results suggest a generalized deficit affecting the structural encoding of faces in patients, as well as the emotion discrimination both in patients and relatives. Finally, these findings lend support to the notion that cortical markers of facial discrimination can be validly considered as vulnerability markers. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
dc.description.funderCONICET
dc.description.funderFINECO
dc.description.funderDiego Portales University
dc.fechaingreso.objetodigital08-04-2024
dc.format.extent9 páginas
dc.fuente.origenWOS
dc.identifier.doi10.1016/j.psychres.2011.07.027
dc.identifier.issn0165-1781
dc.identifier.pubmedidMEDLINE:21824666
dc.identifier.urihttps://doi.org/10.1016/j.psychres.2011.07.027
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/78759
dc.identifier.wosidWOS:000300965100003
dc.information.autorucPsicología;Hurtado E ;S/I;16876
dc.issue.numero1-2
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final26
dc.pagina.inicio18
dc.publisherELSEVIER IRELAND LTD
dc.revistaPSYCHIATRY RESEARCH
dc.rightsacceso restringido
dc.subjectN170
dc.subjectFacial processing
dc.subjectFacial emotion discrimination
dc.subjectBiomarker
dc.subjectSchizophrenia multiplex families
dc.subjectStructural processing
dc.subjectValence
dc.subjectWords
dc.subjectEVENT-RELATED POTENTIALS
dc.subjectFACIAL AFFECT RECOGNITION
dc.subjectSOCIAL COGNITION
dc.subjectBRAIN POTENTIALS
dc.subjectELECTROPHYSIOLOGICAL EVIDENCE
dc.subjectSPATIAL ATTENTION
dc.subjectTIME-COURSE
dc.subjectPERCEPTION
dc.subjectEXPRESSION
dc.subjectWORD
dc.titleThe face and its emotion: Right N170 deficits in structural processing and early emotional discrimination in schizophrenic patients and relatives
dc.typeartículo
dc.volumen195
sipa.codpersvinculados16876
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
2024-04-08. The face and its emotion - Right N170 deficits in structural processing and early emotional discrimination in schizophrenic patients and relatives.pdf
Size:
3.09 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Artículos de revistas