The holistic view on perfusion monitoring in septic shock

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dc.catalogadorpau
dc.contributor.authorHernández P., Glenn
dc.contributor.authorBruhn, Alejandro
dc.contributor.authorCastro, Ricardo
dc.contributor.authorRegueira Heskia, Tomás
dc.date.accessioned2023-05-19T20:25:16Z
dc.date.available2023-05-19T20:25:16Z
dc.date.issued2012
dc.description.abstractPurpose of review: To review recent evidence concerning the interactions between hemodynamic and perfusion parameters during septic shock resuscitation, and to propose some basic foundations for a more comprehensive perfusion assessment. Recent findings: Several recent studies have expanded our knowledge about the physiologic determinants and limitations of currently used perfusion parameters such as central venous oxygen saturation and lactate. Macrohemodynamic, metabolic, peripheral and microcirculatory parameters tend to change in parallel in response to fluid loading during initial resuscitation. In contrast, perfusion markers are poorly correlated in patients who evolve with a persistent circulatory dysfunction. Therefore, assessment of perfusion status based solely on a single parameter can lead to inaccurate or misleading conclusions. Summary: All individual perfusion parameters have extensive limitations to adequately reflect tissue perfusion during persistent sepsis-related circulatory dysfunction. A multimodal approach integrating macrohemodynamic, metabolic, peripheral and eventually microcirculatory perfusion parameters may overcome those limitations. This approach may also provide a thorough understanding on the predominant driving forces of hypoperfusion, and lead to physiologically oriented interventions.
dc.fechaingreso.objetodigital2023-07-06
dc.format.extent7 páginas
dc.fuente.origenORCID
dc.identifier.doi10.1097/MCC.0b013e3283532c08
dc.identifier.issn1070-5295
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/67342
dc.identifier.urihttps://doi.org/10.1097/MCC.0b013e3283532c08
dc.identifier.wosidWOS:000303544600011
dc.information.autorucEscuela de Medicina; Hernández P., Glenn; 0000-0002-3032-4087; 98874
dc.information.autorucEscuela de Medicina; Bruhn, Alejandro; S/I; 741
dc.information.autorucEscuela de Medicina; Castro, Ricardo; 0000-0002-0978-9891; 4537
dc.information.autorucEscuela de Medicina; Regueira Heskia, Tomás; S/I; 18434
dc.issue.numero3
dc.language.isoen
dc.nota.accesoContenido parcial
dc.pagina.final286
dc.pagina.inicio280
dc.revistaCurrent Opinion in Critical Care
dc.rightsacceso restringido
dc.subjectCentral venous oxygen saturation
dc.subjectFluid challenge
dc.subjectLactate
dc.subjectMicrocirculation
dc.subjectTissue perfusion
dc.subject.ddc610
dc.subject.deweyMedicina y saludes_ES
dc.subject.ods03 Good health and well-being
dc.subject.odspa03 Salud y bienestar
dc.titleThe holistic view on perfusion monitoring in septic shockes_ES
dc.typeartículo
dc.volumen18
sipa.codpersvinculados98874
sipa.codpersvinculados741
sipa.codpersvinculados4537
sipa.codpersvinculados18434
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