Rectal diffuse large B cell lymphoma appearing after immunosuppression for ulcerative colitis. Report of one case
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Date
2017
Journal Title
Journal ISSN
Volume Title
Publisher
SOC MEDICA SANTIAGO
Abstract
Primary colorectal lymphoma is a rare form of presentation of gastrointestinal tract lymphomas. Inflammatory bowel disease and its treatment are risk factors for its development. We report a 47-year-old male patient with Ulcerative Colitis of two years of evolution, treated initially with azathioprine and later on with infliximab. Due to a relapse in symptoms after the second dose of infliximab, a new coloncoscopy was performed showing a rectal ulcerative lesion, corresponding to a large cell Non-Hodgkin's Lymphoma. The patient was successfully treated with RCHOP chemotherapy (Rituximab cyclophosphamide doxorubicin vincristine prednisone). He is currently in disease remission.
Description
Keywords
Colitis, Ulcerative, Crohn Disease, Inflammatory Bowel Disease, Lymphoma, Large B-Cell, Diffuse, PRIMARY COLONIC LYMPHOMA, NON-HODGKINS-LYMPHOMA, EPSTEIN-BARR-VIRUS, MALIGNANT-LYMPHOMA, RISK, AZATHIOPRINE, ASSOCIATION, CANCER, INFLAMMATION, THIOPURINES