A Novel Earwax Self-Sampling Device: A Feasibility Study

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dc.contributor.authorHerane-Vives, Andres
dc.contributor.authorSandoval, Rodrigo
dc.contributor.authorOrtega, Lorena
dc.contributor.authorEspinoza, Susana
dc.contributor.authorCleare, Anthony
dc.contributor.authorHayes, Alexander
dc.contributor.authorOrtuzar, Esteban
dc.contributor.authorValdenegro, Tomas
dc.contributor.authorAguilo, Bruno
dc.contributor.authorBenoehr, Jan
dc.contributor.authorArnone, Danilo
dc.date.accessioned2025-01-20T22:19:41Z
dc.date.available2025-01-20T22:19:41Z
dc.date.issued2021
dc.description.abstract(1) Background: Earwax might provide the long-term concentration of substances that are altered in chronic diseases. Standardised earwax extraction has to be exclusively performed by clinicians. We investigated the safety, reliability, and tolerance of a novel self-sampling earwax device in comparison with a clinical method; (2) Methods: We compared the reliability between both methods in a longitudinal study. We first cleaned both ears at baseline in 37 controls. Secondly, we obtained a sample a month after by extracting earwax from the right ear with a novel self-sampling device, and from the left ear by using the clinical method. Reliability of both methods was measured by coefficients of variation; (3) Results: The weight of the baseline samples was not significantly different between ear sides. The reliability of the two methods was not significantly different. The self-extraction method removed eight times more earwax than the clinical method. The new method proved to be well tolerated; (4) Conclusions: The novel device was as reliable as the clinical method in sampling earwax. In view of its practicality, safety, tolerability and efficiency, the new method may have clinical applications at a reduced cost.
dc.fuente.origenWOS
dc.identifier.doi10.3390/app11114882
dc.identifier.eissn2076-3417
dc.identifier.urihttps://doi.org/10.3390/app11114882
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/94603
dc.identifier.wosidWOS:000659557600001
dc.issue.numero11
dc.language.isoen
dc.revistaApplied sciences-basel
dc.rightsacceso restringido
dc.subjectself-sampling earwax device
dc.subjectclinical method
dc.subjectcotton swabs
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleA Novel Earwax Self-Sampling Device: A Feasibility Study
dc.typeartículo
dc.volumen11
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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