Analysis of the passive biomechanical behavior of a sheep-specific aortic artery in pulsatile flow conditions

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dc.contributor.authorGarcia-Herrera, Claudio M.
dc.contributor.authorCuevas, Alvaro A.
dc.contributor.authorCelentano, Diego J.
dc.contributor.authorNavarrete, Alvaro
dc.contributor.authorAranda, Pedro
dc.contributor.authorHerrera, Emilio
dc.contributor.authorUribe, Sergio
dc.date.accessioned2025-01-20T23:54:36Z
dc.date.available2025-01-20T23:54:36Z
dc.date.issued2021
dc.description.abstractIn this work, a novel numerical-experimental procedure is proposed, through the use of the Cardiac Simulation Test (CST), device that allows the exposure of the arterial tissue to in-vitro conditions, mimicking cardiac cycles generated by the heart. The main goal is to describe mechanical response of the arterial wall under physiological conditions, when it is subjected to a variable pressure wave over time, which causes a stress state affecting the biomechanical behavior of the artery wall. In order to get information related to stress and strain states, numerical simulation via finite element method, is performed under a condition of systolic and diastolic pressure. The description of this methodological procedure is performed with a sample corresponding to a sheep aorta without cardiovascular pathologies. There are two major findings: the evaluation of the mechanical properties of the sheep aorta through the above-mentioned tests and, the numerical simulation of the mechanical response under the conditions present in the CST. The results state that differences between numerical and experimental circumferential stretch in diastole and systole to distinct zones studied do not exceed 1%. However, greater discrepancies can be seen in the distensibility and incremental modulus, two main indicators, which are in the order of 30%. In addition, numerical results determine an increase of the principal maximum stress and strain between the case of systolic and diastolic pressure, corresponding to 31.1% and 14.9% for the stress and strain measurement respectively; where maximum values of these variables are located in the zone of the ascending aorta and the aortic arch.
dc.fuente.origenWOS
dc.identifier.doi10.1080/10255842.2021.1872549
dc.identifier.eissn1476-8259
dc.identifier.issn1025-5842
dc.identifier.urihttps://doi.org/10.1080/10255842.2021.1872549
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/95036
dc.identifier.wosidWOS:000609607900001
dc.issue.numero11
dc.language.isoen
dc.pagina.final1241
dc.pagina.inicio1228
dc.revistaComputer methods in biomechanics and biomedical engineering
dc.rightsacceso restringido
dc.subjectArteries
dc.subjectaorta
dc.subjectbiomechanical model
dc.subjectpulsatile flow
dc.subjectcardiac simulation test (CST)
dc.subjectfinite element method (FEM)
dc.subjectuniaxial tensile test
dc.titleAnalysis of the passive biomechanical behavior of a sheep-specific aortic artery in pulsatile flow conditions
dc.typeartículo
dc.volumen24
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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