Prevalence of Epstein Barr virus infection in healthy individuals in Santiago, Chile

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dc.contributor.authorFerres, M
dc.contributor.authorPrado, P
dc.contributor.authorOvalle, J
dc.contributor.authorFuentes, R
dc.contributor.authorVillarroel, L
dc.contributor.authorFerreccio, C
dc.contributor.authorVial, P
dc.date.accessioned2024-01-10T12:41:44Z
dc.date.available2024-01-10T12:41:44Z
dc.date.issued1995
dc.description.abstractTo study the rate of infection by Epstein Barr virus (EBV) in Santiago, Chile, the prevalence of antibody to the viral capsid antigen (VCA-lgG) was determined in a group of 663 healthy individuals grouped by age and socioeconomic level (SEL). In addition, several risk factors for infection were studied. VCA-lgG was determined by ELISA. The total prevalence was 76,7%. When grouped by age and SEL, 50% of the children from low and medium SEL had been already infected by the age two, compared to 5,9% in the high SEL (p<0.01). However, by age twenty, 90% of the total sample had already specific antibodies to EBV. Age and number of household members were positively associated with the infection. High socioeconomic level represented a delay factor in the acquisition of the virus, (p<0.01). These results show that EBV infection is frequent in Santiago, occurring early in childhood among medium and low SEL. Hence, the classical infectious mononucleosis should be recognized more frequently among adolescents and young adults belonging to high SEL, while the clinical spectrum of associated manifestations different from the typical mononucleosis syndrome should be investigated among these exposed in early age.
dc.format.extent6 páginas
dc.fuente.origenWOS
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:8733260
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77445
dc.identifier.wosidWOS:A1995TV10100001
dc.information.autorucMedicina;Ferreccio C;S/I;99684
dc.information.autorucMedicina;Ferrés M;S/I;66180
dc.issue.numero12
dc.language.isoes
dc.nota.accesoSin adjunto
dc.pagina.final1452
dc.pagina.inicio1447
dc.publisherSOC MEDICA SANTIAGO
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsregistro bibliográfico
dc.subjectEpstein-Barr virus
dc.subjectserodiagnosis
dc.subjectantibodies
dc.subjectenzyme-linked immunosorbent assay
dc.subjectinfectious mononucleosis
dc.subjectCHILDREN
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titlePrevalence of Epstein Barr virus infection in healthy individuals in Santiago, Chile
dc.typeartículo
dc.volumen123
sipa.codpersvinculados99684
sipa.codpersvinculados66180
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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