Fast Heating-Assisted One-Pot Copper-Catalyzed Sulfonylation and Sulfochlorination of Styrenes

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dc.contributor.authorSaavedra-Olavarria, Jorge
dc.contributor.authorHermosilla-Ibanez, Patricio
dc.contributor.authorAlmodovar, Iriux
dc.contributor.authorPerez, Edwin G.
dc.date.accessioned2025-01-20T21:09:04Z
dc.date.available2025-01-20T21:09:04Z
dc.date.issued2022
dc.description.abstractHere, a strategy for the synthesis under fast-heating conditions of vinyl sulfones and beta-chlorosulfones from styrene derivatives, tosyl chloride (TsCl) as sulfonyl and chlorine source, and CuBr-neocuproine as the catalytic system is reported. The reaction occurs through an atom transfer radical addition (ATRA) mechanism to generate the sulfochlorinated adducts followed by E2 elimination to generate the vinyl sulfones. This methodology allows a wide range of vinyl sulfones and beta-chlorosulfones to be obtained using inexpensive reagents in one and five minutes respectively. These reactions appear as an interesting fast and easy-to-handle alternative to obtain these compounds.
dc.fuente.origenWOS
dc.identifier.doi10.1002/ejoc.202101526
dc.identifier.eissn1099-0690
dc.identifier.issn1434-193X
dc.identifier.urihttps://doi.org/10.1002/ejoc.202101526
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/93510
dc.identifier.wosidWOS:000788183200001
dc.issue.numero29
dc.language.isoen
dc.revistaEuropean journal of organic chemistry
dc.rightsacceso restringido
dc.subjectCatalysis
dc.subjectCopper
dc.subjectOne pot synthesis
dc.subjectSulfochlorination
dc.subjectSulfonylation
dc.titleFast Heating-Assisted One-Pot Copper-Catalyzed Sulfonylation and Sulfochlorination of Styrenes
dc.typeartículo
dc.volumen2022
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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