Hyperbaric oxygen therapy in a patient with autosomal dominant polycystic kidney disease with a perinephritic abscess

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dc.contributor.authorVega, Jorge
dc.contributor.authorGoecke, Helmuth
dc.contributor.authorManriquez, Francisco
dc.contributor.authorEscobar, Carlos
dc.contributor.authorEscobar, Max
dc.contributor.authorVidela, Christian
dc.contributor.authorSantamarina, Mario
dc.contributor.authorEcheverria, Carlos
dc.contributor.authorJavier Guarda, Francisco
dc.date.accessioned2025-01-21T00:02:43Z
dc.date.available2025-01-21T00:02:43Z
dc.date.issued2011
dc.description.abstractA 68-year-old female in hemodialysis due to autosomal dominant polycystic kidney disease underwent resection of cysts in her right kidney via a laparoscopic approach due to abdominal pain. Three weeks after surgery, she was admitted with sepsis. A CT scan showed a large abscess around the right kidney. Percutaneous drainage of abscess was performed. The pus smear showed Gram-positive cocci and the culture contained methicillin-resistant Staphylococcus aureus. Ciprofloxacin, clindamycin and vancomycin were given. In the 3 weeks following admission, she remained febrile and septic and showed a progressive deterioration in her general condition, along with malnutrition and persistent drainage of purulent material from her right flank. The antibiotic therapy was changed to vancomycin, metronidazole and meropenem, but no improvement was observed. Because of the high risk associated with carrying out an open nephrectomy, we decided to use hyperbaric oxygen therapy (HBOT) as a potentially useful measure to control her infection. The patient underwent 26 daily sessions of 100% hyperbaric oxygen (2.5 atm). The use of HBOT induced a notable break in the clinical course of this patient's retroperitoneal infection. She was discharged after day 58 without any signs of inflammatory activity, and she has not presented reactivation of infection since then. We think that this case suggests that this therapy could be a new therapeutic tool in the management of patients with similar clinical features when all other therapeutic measures have failed. We did not find any other reports of the use of HBOT in infections of renal cysts.
dc.fuente.origenWOS
dc.identifier.doi10.1007/s10157-010-0348-2
dc.identifier.eissn1437-7799
dc.identifier.issn1342-1751
dc.identifier.urihttps://doi.org/10.1007/s10157-010-0348-2
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/95433
dc.identifier.wosidWOS:000287452800022
dc.issue.numero1
dc.language.isoen
dc.pagina.final146
dc.pagina.inicio141
dc.revistaClinical and experimental nephrology
dc.rightsacceso restringido
dc.subjectHyperbaric oxygen therapy
dc.subjectPolycystic kidney disease
dc.subjectPerinephritic abscess
dc.subjectRetroperitoneal abscess
dc.subjectSepsis
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa03 Salud y bienestar
dc.titleHyperbaric oxygen therapy in a patient with autosomal dominant polycystic kidney disease with a perinephritic abscess
dc.typeartículo
dc.volumen15
sipa.indexWOS
sipa.trazabilidadWOS;2025-01-12
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