Frequency of subclinical thyroid problems among women during the first trimester of pregnancy

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dc.contributor.authorMosso M, Lorena
dc.contributor.authorMartinez G, Alejandra
dc.contributor.authorPaulina Rojas, Maria
dc.contributor.authorMargozzini, Paula
dc.contributor.authorSolari, Sandra
dc.contributor.authorLyng, Trinidad
dc.contributor.authorAndres Ortiz, Juan
dc.contributor.authorCarvajal, Jorge
dc.date.accessioned2024-01-10T12:39:06Z
dc.date.available2024-01-10T12:39:06Z
dc.date.issued2012
dc.description.abstractBackground: Thyroid hormones play an important role in fetal neural and cognitive development. Therefore thyroid abnormalities should be detected and treated early during pregnancy. Aim: To assess the frequency and risk factors for functional thyroid disorders during the first trimester of pregnancy. Material and Methods: A blood sample was obtained from women during their first trimester of pregnancy, consulting in a prenatal care facility. Women with known thyroid diseases were excluded from the study. Thyroid stimulating hormone (TSH), total thyroxine (T4) and free thyroxine (fT4) were measured by electrochemoluminiscence. Antithyroid peroxidase antibodies (anti TPO) were measured by enzyme immunoassay. Results: Five hundred and ten women aged 25.7 +/- 6.6 years were assessed. The frequency of clinical hypothyroidism was 0.6%, subclinical hypothyroidism 35.3% and clinical hyperthyroidism 1%. Five percent of women with hypothyroidism and 3.5% of euthyroid women had positive anti TPO antibodies. There was no association between the frequency of thyroid diseases and risk factors for thyroid diseases. Conclusions: There is a high frequency of subclinical thyroid diseases among women consulting in this prenatal care clinic. (Rev Med Chile 2012; 140: 1401-1408).
dc.fechaingreso.objetodigital2024-05-29
dc.format.extent8 páginas
dc.fuente.origenWOS
dc.identifier.doi10.4067/S0034-98872012001100004
dc.identifier.eissn0717-6163
dc.identifier.issn0034-9887
dc.identifier.pubmedidMEDLINE:23677185
dc.identifier.urihttps://doi.org/10.4067/S0034-98872012001100004
dc.identifier.urihttps://repositorio.uc.cl/handle/11534/77145
dc.identifier.wosidWOS:000312626000004
dc.information.autorucMedicina;Carvajal J ;S/I;3345
dc.information.autorucMedicina;Margozzini P ;S/I;63265
dc.information.autorucMedicina;Martinez A;S/I;1003862
dc.information.autorucMedicina;Mosso L;S/I;88201
dc.information.autorucMedicina;Ortiz J;S/I;66283
dc.information.autorucMedicina;Rojas M;S/I;84632
dc.information.autorucMedicina;Solari S ;S/I;1871
dc.issue.numero11
dc.language.isoes
dc.nota.accesoContenido completo
dc.pagina.final1408
dc.pagina.inicio1401
dc.publisherSOC MEDICA SANTIAGO
dc.revistaREVISTA MEDICA DE CHILE
dc.rightsacceso abierto
dc.subjectPregnancy
dc.subjectReference values
dc.subjectThyroid function tests
dc.subjectThyroid hormones
dc.subjectDYSFUNCTION
dc.subjectHYPOTHYROXINEMIA
dc.subjectHYPERTHYROIDISM
dc.subject.ods05 Gender Equality
dc.subject.ods03 Good Health and Well-being
dc.subject.odspa05 Igualdad de género
dc.subject.odspa03 Salud y bienestar
dc.titleFrequency of subclinical thyroid problems among women during the first trimester of pregnancy
dc.typeartículo
dc.volumen140
sipa.codpersvinculados3345
sipa.codpersvinculados63265
sipa.codpersvinculados1003862
sipa.codpersvinculados88201
sipa.codpersvinculados66283
sipa.codpersvinculados84632
sipa.codpersvinculados1871
sipa.indexWOS
sipa.indexScopus
sipa.trazabilidadCarga SIPA;09-01-2024
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